Design of New Condensation System by the Facilitated Permeation through the Porous Block Copolymer Membrane

通过双环草内酰胺3的阴离子聚合，合成了一种以聚酰胺(2)为外链、聚氧乙烯为内链的新型ABA型嵌段共聚物(1)。以聚氧乙二醇和过量的甲苯-2，4-二异氰酸酯为原料，合成了端异氰酸酯基聚氧乙烯。将1，4-二氯乙烷与聚氧乙二醇的混合物浇铸成溶液，室温干燥，然后用水浸泡、漂洗，制得了多孔膜。在肌红蛋白的溶质排斥试验中，渗透液的浓度远高于饲料中的浓度。这种特殊的凝聚不仅取决于多孔膜的浇注条件，而且还取决于渗透条件，如压差、机械搅拌、蛋白质溶液的初始浓度和电解液的添加。目前的运输系统被认为是蛋白质在多孔膜上的快速吸附和由较低压力驱动的运输的微妙结合的结果。

A new ABA-type block copolymer (1) composed of polyamide (2) as outer segments and polyoxyethylene as an inner segment was prepared by the anionic polymerization of a bicyclic oxalactam 3. A polyoxyethylene having terminal isocyanate groups (4) was used as an activator obtained from polyoxyethylene glycol and an excess of tolylene-2,4-diisocyanate. A porous membrane was prepared by casting the solution of the mixture of 1 with polyoxyethylene glycol and drying up at room temperature, followed by immersing and rinsing in water. In the solute rejection test for myoglobin, the concentration of the permeate was found to be much higher than that in the feed. Such peculiar condensation was much dependent not only upon the casting conditions for the porous membrane, but also upon permeation conditions such as the pressure difference, mechanical stirring, the initial concentration of protein solutions, and the addition of electolyte. The present transport system is presumed to result from the delicate combination of the rapid adsorption of proteins onto the porous membrane and their transport driven by the lower pressure.