Simple Synthesis of a Large Amount of a Biodegradable Polyamide and Design of Its processing and Degradation systems

2-吡咯烷酮在高真空线上的纯化和聚合是制备高分子量尼龙4的必要条件，但同时也影响了其大规模制备。为了扩大2-吡咯烷酮的聚合规模，本工作在预纯化的氮气气氛中进行了这些过程。对2-吡咯烷酮进行阴离子聚合，一次可得到80克以上的低分子量尼龙4。2-吡咯烷酮经减压蒸馏纯化，随后在活化分子筛上干燥，而不是在使用前通过其水合物的重结晶。另一方面，2-吡咯烷酮的纯化是制备高分子量尼龙必不可少的步骤，首先是通过其水合物的再结晶，然后在分子筛上进行蒸馏和干燥。因此，在干燥的氮气气氛下，而不是在高真空线下，一次聚合可以得到100克以上的高分子量尼龙4。通过对尼龙4的酰基内酰胺型链端进行化学改性，提高了尼龙4的热稳定性。

The strict procedures for the purification and polymerization of 2-pyrrolidone in high vacuum line are necessary for the preparation of high molecular weight nylon4, which disturb its preparation on a large scale at a time. In order to scale up the polymerization of 2-pyrrolidone, the procedures were performed in an atmosphere of prepurified nitrogen in the present work.More than 80 grams of low molecular weight nylon4 was obtained at a time on the anionic polymerization of 2-pyrrolidone which was purified by the distillation under reduced pressure and the subsequent drying on the activated molecular sieves, but not through the recrystallization of its hydrate before use. On the other hand, the purification of 2-pyrrolidone through the recrystallization of its hydrate subsequently by the distillation and drying on the molecular sieves was essential for the preparation of the high molecular weight nylon4. Thus more than 100g of the high molecular weight nylon4 was obtained on one polymerization procedure under dry nitrogen atmosphere but not in a high vacuum line.The thermal stability of nylon4 was found to increase through the chemical modification of its acyllactam-type chain end.