Effects of ionophore antibiotics on rumen fermentation

离子载体抗生素对瘤胃发酵的影响

• 批准号: 61560326
• 负责人: HOSHINO Sadao
• 金额: $ 1.34万
• 依托单位: Mie University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61560326/
• 关键词: Ionophore; Rumen fermentation; Methane production; Propionate proportion; Electron flow; Lactate-utilizable bacteria; Microbial yield; 12指腸内容物; サリノマイシン; 育成牛; 細菌叢; 微生物増殖量; 消化率; プロトゾア; 水素添加; モネンシン; 肥育牛; 黒毛和種; 哺育牛; ルーメン繊毛; VFA組成; 消化管内容の移

Various experiments were conducted with ionophore antibiotics such as salinomycin(SL), monensin(MN) and portomycin(PT). The principal results obtained are as follows: 1. Addition of SL reduced gas production consisting mainly of CO_2 and CH_4, and transiently increased H_2 production in in vitro fermentation with sheep rumen fluid, but with rumen fluid from animals adapted to SL there were no transient increases in H_2 production. 2. Addition of either SL, MN or PT to concentrate feeds for growing calves and steers improved feed requirement, with concomitant changes in rumen fermentation towards more propionate and -amino nitrogen, and less acetate, butyrate and ammonia. 3. These alterations in rumen fermentation were in good agreement with those in numbers of starch-, lactateand protein-utilizable bacteria and of protozoa. 4. Effects of ionophore often fluctuated, presumably due to the development of resistant microbial population. This was shown by variations of rumen protozoa before, during and after ionophore supplement in sheep rumen. 5. Ionophore depressed microbial proliferation in the rumen, but did not affect digestibility of feeds appreciably.

用离子载体抗生素如盐霉素（SL）、莫能菌素（MN）和泊洛霉素（PT）进行各种实验。主要结果如下：1.在绵羊瘤胃液体外发酵中，添加SL降低了主要由CO_2和CH_4组成的气体的产生，并短暂增加了H_2的产生，但在适应SL的动物瘤胃液中，H_2的产生没有短暂增加。2.添加SL，MN或PT的浓缩饲料生长的小牛和公牛改善饲料需求，伴随着瘤胃发酵的变化，对更多的丙酸和氨基氮，乙酸，丁酸和氨。3.瘤胃发酵的这些变化与淀粉、乳酸和蛋白质利用细菌和原生动物的数量变化一致。4.离子载体的影响往往波动，可能是由于耐药微生物种群的发展。绵羊瘤胃内离子载体添加前后瘤胃原虫数量的变化表明了这一点。5.离子载体抑制瘤胃微生物增殖，但对饲料消化率无明显影响。

项目成果

Kobayashi Yasuo: Nutrition Reports International. 38. 987-999 (1988)

小林康夫：国际营养报告。

脇田正彰: 日本畜産学会報. 58. 396-402 (1987)

Masaaki Wakita：日本动物科学会通报 58. 396-402 (1987)。

Wakita Masaaki: "Effects of salinomycin on the gas production by sheep rumen contents in vitro" Journal of Animal Physiology and Animal Nutrition. 56. 243-251 (1986)

Wakita Masaaki：“盐霉素对绵羊瘤胃内容物体外产气的影响”《动物生理学和动物营养学杂志》。

Kobayashi,Yasuo: Nutrition Reports International. 38. 987-999 (1988)

小林亚索：国际营养报告。

Wakita Masaaki: "Effects of salinomycin on feed conversion and ruminal fluid characteristics in fattening Japanese Black cattle" Japanese Journal of Zootechnical Science. 58. 467-473 (1987)

Wakita Masaaki：“盐霉素对日本黑牛育肥过程中饲料转化率和瘤胃液特性的影响”《日本动物技术科学杂志》。