Studies on the host resistance to infection with larval cyclophyllidean cestodes
Studies on the host resistance to infection with larval cyclophyllidean cestodes
批准号:
61560331
负责人:
OKU Yuzaburo
金额:
$0.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1987
中文摘要
1. 3个带绦虫(Hokkaido-Rattus、Malaysia-Rattus和Hokkaido-Clethrionomys)分离株在部分野生和实验啮齿类动物中,特别是在大鼠和红腹竹鼠中的繁殖力存在差异。2.对经口感染包虫虫卵有抵抗力的鼠类,对腹腔接种未成熟囊尾蚴敏感。3.部分实验动物和C.红口绦虫对经口感染虫卵或腹腔接种多房棘球绦虫和粗头绦虫幼虫的影响。4.在可的松处理、X射线照射和环磷酰胺处理的小鼠中,T。带形绦虫的存活时间长于眼镜蛇毒因子处理的、角叉菜胶处理的和对照小鼠。5.鸡蛋E。由于多房性肠梗阻对饲养员的危害很大,因此对狗进行了手术,在狗的腹膜腔中产生了一个分离的小肠。在分离的小肠中,注射的大肠杆菌原头节。多房虫不发育,短期内死亡。6.戈登仓鼠经口感染E. multilocularis和T.粗头鱼在宿主的小肠中,E.多室层发育,成熟分节段发育。T.在仓鼠体内产卵。7.利用近交系小鼠进行实验和体外实验。
英文摘要
1. Infectivity of three isolates of Taenia taeniaeformis (Hokkaido-Rattus, Malaysia-Rattus and Hokkaido-Clethrionomys isolates) varied in some wild and experimental rodents, especially rat and Clethrionomys rufocanus. 2. The rodents, which were resistant to oral infection with eggs of Taenia hydatigena, were susceptible to intraperitoneal inoculation of immature cysticercus. 3. Significant difference was observed in susceptibility of some experimental animals and C. rufocanus to oral infection of eggs or to intraperitoneal inoculation of larvae of Echinococcus multilocularis and Taenia crassiceps. 4. In cortisone-treated, X-ray-irradiated and cyclophosphamide-treated mice, the larvae of T. taeniaeformis survived for longer period than that in cobra venom factor-treated, carrageenan-treated and control mice. 5. Egg of E. multilocularis is very danger to breeders, so dogs were operated surgically, so a separated small intestine were produced in the perotoneal cavity of the dog. In the separated small intestine, the injected protoscolices of E. multilocularis did not developed, and were dead in short period. 6. Gorden hamsters were infected orally with larvae of E. multilocularis and T. crassiceps. In the small intestine of the host, E. multilocularis were developed, and mature segument were observed. T. crassiceps produced eggs in hamsters. 7. Experiments using inbred mouse and in vitro experiments are carrying out.
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
宮地俊: 寄生虫学雑誌. 36(1.補). 43 (1987)
宫地舜:《寄生虫学杂志》36(1.补充)43(1987)。
DOI:
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发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
野中成晃: 寄生虫学雑誌. 36(1.補). 43-44 (1987)
N. Nonaka:《寄生虫学杂志》36(1.补充)43-44(1987)。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
In silico analysis of full-length rich cDNA library of Echinococcus multilocularis, molecular bases of the parasite growth and development, and vaccine
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批准号:20380164
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.31万
-
财政年份:2008
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负责人:OKU Yuzaburo
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依托单位:
Environmental adaptation of Taeniods in Latin America
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批准号:09041137
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.49万
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财政年份:1998
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负责人:OKU Yuzaburo
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依托单位:
Control of Echinococcus multilocularis in rural area by anthelminthics application for definitive hosts
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批准号:07557204
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$4.29万
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财政年份:1995
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负责人:OKU Yuzaburo
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依托单位:
Environmental adaptation of Echinococcus in South America
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批准号:06041005
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$10.05万
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财政年份:1994
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负责人:OKU Yuzaburo
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依托单位:
海外基金