Studies on the host resistance to infection with larval cyclophyllidean cestodes

1. 三种带绦虫分离株（北海道-家鼠、马来西亚-家鼠和北海道-家鼠分离株）在一些野生和实验啮齿类动物中的传染性存在差异，尤其是大鼠和红绒带绦虫。2. 小鼠对含带绦虫虫卵的口腔感染具有抗性，但对未成熟囊虫腹腔接种敏感。3. 部分实验动物和红棘球绦虫对卵口感染和腹腔接种多房棘球绦虫和带绦虫幼虫的易感性有显著差异。4. 在可的松、x射线和环磷酰胺处理的小鼠中，带绦虫幼虫的存活时间长于眼镜蛇毒因子处理、卡拉胶处理和对照小鼠。5. 多房棘球绦虫的卵对饲养者来说非常危险，所以对狗进行了手术，在狗的腹股腔中产生了一个分离的小肠。在分离的小肠内，注射的多房棘原脊柱不发育，短时间内死亡。6. 采用多房小仓鼠和粗腹小仓鼠幼虫口腔感染试验。在寄主小肠内发育有多房绦虫，可见成熟节段。绦虫在仓鼠体内产卵。7. 正在进行近交系小鼠实验和体外实验。

1. Infectivity of three isolates of Taenia taeniaeformis (Hokkaido-Rattus, Malaysia-Rattus and Hokkaido-Clethrionomys isolates) varied in some wild and experimental rodents, especially rat and Clethrionomys rufocanus. 2. The rodents, which were resistant to oral infection with eggs of Taenia hydatigena, were susceptible to intraperitoneal inoculation of immature cysticercus. 3. Significant difference was observed in susceptibility of some experimental animals and C. rufocanus to oral infection of eggs or to intraperitoneal inoculation of larvae of Echinococcus multilocularis and Taenia crassiceps. 4. In cortisone-treated, X-ray-irradiated and cyclophosphamide-treated mice, the larvae of T. taeniaeformis survived for longer period than that in cobra venom factor-treated, carrageenan-treated and control mice. 5. Egg of E. multilocularis is very danger to breeders, so dogs were operated surgically, so a separated small intestine were produced in the perotoneal cavity of the dog. In the separated small intestine, the injected protoscolices of E. multilocularis did not developed, and were dead in short period. 6. Gorden hamsters were infected orally with larvae of E. multilocularis and T. crassiceps. In the small intestine of the host, E. multilocularis were developed, and mature segument were observed. T. crassiceps produced eggs in hamsters. 7. Experiments using inbred mouse and in vitro experiments are carrying out.