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Studies on the host resistance to infection with larval cyclophyllidean cestodes

Studies on the host resistance to infection with larval cyclophyllidean cestodes
寄主对环叶绦虫幼虫感染的抵抗力研究
批准号:
61560331
负责人:
OKU Yuzaburo
金额:
$0.96万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1986
资助国家:
日本
项目状态:
已结题
起止时间:
1986 至 1987

项目摘要

项目成果

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中文摘要
翻译
1.三种带绦虫分离株(北海道-Rattus、马来西亚-Rattus和北海道-Cleereonomys)在一些野生和实验啮齿动物中的感染性不同,特别是大鼠和红纹夜蛾。2.对包虫虫卵具有抵抗力的啮齿动物,对未成熟囊虫的腹腔接种易感。3.部分实验动物和红色毛圆线虫对经口感染虫卵或经腹腔接种多房棘球绦虫和粗隆带绦虫幼虫的敏感性有显著差异。4.经可的松、X射线照射和环磷酰胺处理的小鼠,其幼虫存活时间明显长于眼镜蛇毒素组、角叉菜胶组和对照组。5.多房棘球绦虫卵对饲养者有很大的危险性,因此对狗进行了外科手术,在狗的腹膜腔内产生了一个分离的小肠。在分离的小肠中,注射的多房棘球绦虫的原头节没有发育,并在短期内死亡。6.用多房棘球绦虫幼虫和粗头乳头虫幼虫对Gorden仓鼠进行口服感染。在寄主的小肠中,发育出多房棘球绦虫,并观察到成熟的节段。粗毛毛滴虫在仓鼠体内产卵。7.进行了近交系小鼠实验和体外实验。
英文摘要
1. Infectivity of three isolates of Taenia taeniaeformis (Hokkaido-Rattus, Malaysia-Rattus and Hokkaido-Clethrionomys isolates) varied in some wild and experimental rodents, especially rat and Clethrionomys rufocanus. 2. The rodents, which were resistant to oral infection with eggs of Taenia hydatigena, were susceptible to intraperitoneal inoculation of immature cysticercus. 3. Significant difference was observed in susceptibility of some experimental animals and C. rufocanus to oral infection of eggs or to intraperitoneal inoculation of larvae of Echinococcus multilocularis and Taenia crassiceps. 4. In cortisone-treated, X-ray-irradiated and cyclophosphamide-treated mice, the larvae of T. taeniaeformis survived for longer period than that in cobra venom factor-treated, carrageenan-treated and control mice. 5. Egg of E. multilocularis is very danger to breeders, so dogs were operated surgically, so a separated small intestine were produced in the perotoneal cavity of the dog. In the separated small intestine, the injected protoscolices of E. multilocularis did not developed, and were dead in short period. 6. Gorden hamsters were infected orally with larvae of E. multilocularis and T. crassiceps. In the small intestine of the host, E. multilocularis were developed, and mature segument were observed. T. crassiceps produced eggs in hamsters. 7. Experiments using inbred mouse and in vitro experiments are carrying out.
期刊论文(2)
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会议论文
宮地俊: 寄生虫学雑誌. 36(1.補). 43 (1987)
宫地舜:《寄生虫学杂志》36(1.补充)43(1987)。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
野中成晃: 寄生虫学雑誌. 36(1.補). 43-44 (1987)
N. Nonaka:《寄生虫学杂志》36(1.补充)43-44(1987)。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
In silico analysis of full-length rich cDNA library of Echinococcus multilocularis, molecular bases of the parasite growth and development, and vaccine
  • 批准号:
    20380164
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 资助金额:
    $12.31万
  • 财政年份:
    2008
  • 负责人:
    OKU Yuzaburo
  • 依托单位:
Environmental adaptation of Taeniods in Latin America
  • 批准号:
    09041137
  • 项目类别:
    Grant-in-Aid for Scientific Research (B).
  • 资助金额:
    $7.49万
  • 财政年份:
    1998
  • 负责人:
    OKU Yuzaburo
  • 依托单位:
Control of Echinococcus multilocularis in rural area by anthelminthics application for definitive hosts
  • 批准号:
    07557204
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
  • 资助金额:
    $4.29万
  • 财政年份:
    1995
  • 负责人:
    OKU Yuzaburo
  • 依托单位:
Environmental adaptation of Echinococcus in South America
  • 批准号:
    06041005
  • 项目类别:
    Grant-in-Aid for international Scientific Research
  • 资助金额:
    $10.05万
  • 财政年份:
    1994
  • 负责人:
    OKU Yuzaburo
  • 依托单位:
海外基金