Environmental adaptation of Taeniods in Latin America
Environmental adaptation of Taeniods in Latin America
批准号:
09041137
负责人:
OKU Yuzaburo
金额:
$7.49万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B).
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999
中文摘要
寄生虫适应环境,在疫区趋于稳定。细粒棘球绦虫在世界范围内均有分布,尤其是在养羊大国,是重要的人畜共患病。猪带绦虫也是一种人畜共患病,在拉丁美洲引起脑囊虫病。种内变异在E.在世界上的颗粒,有许多变异的报道。本文报道了细粒棘球绦虫、沃氏棘球绦虫和猪带绦虫在拉丁美洲的流行状况和环境适应性。我们对洪都拉斯和巴西的猪进行了猪带绦虫调查,但在巴西很难找到阳性病例。乌拉圭最重要的产业是畜牧业。E. 1991年和1999年测定了绵羊粒细胞体。在乌拉圭,对E. 1991- 1992年改变了granulosus。1998- 1999年,绵羊中的流行率急剧下降。1998年很难找到受感染的狗。因此,我们尝试制备单克隆抗体,为建立一种新的高灵敏度的犬免疫诊断方法奠定基础。单克隆抗体对多房棘球绦虫有一定的诊断价值。E.在乌拉圭的颗粒没有显示在我们的样品从羊。我们试图建立E. granulosus和E. vogeli,仅对E. vogeli使用用泼尼松龙处理的蒙古沙鼠。本文观察了沙鼠小肠的发育过程。
英文摘要
Parasites adapt to their environment, and become steady in endemic area. Echinococcus granulosus are distributed in world wide, especially sheep breeding countries, and important zoonosis in such countries. Taenia solium is also zoonosis, and cause the cerebral cysticercosis in Latin America. Intraspecific variations are prominent in E. granulosus in the world, there are many variations are reported. Epidemiologicalstatus and environmental adaptation of Echinococcus granulosus, E, vogeli and Taenia solium in Latin America were studied. We carried out a survey of Taenia solium in pigs of Honduras and Brazil, but very difficult to find positive cases in Brazil. Most important industry of Uruguay is livestock industry. Prevalence of E. granulosus in sheep was determined in 1991 and 1999. In Uruguay, Control measure against E. granulosus was changed in 1991-2. The prevalence in sheep had been drastically reduced in 1998-9. It is very difficult to find infected dogs in 1998. So, we tried to produce monoclonal antibodies for developing a new high sensitive immunodiagnostic method for dogs using monoclonal antibodies. A monoclonal antibody was useful for Echinococcus multilocularis. Intraspecific variations of E. granulosus in Uruguay were not shown in our samples from sheep. We tried to establish alternative definitive hosts of E. granulosus and E. vogeli, and succeed only for E. vogeli using Mongolian jirds treated with predonisolone. The development in the small intestine were observed in jirds.
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NONAKA N.: "Monitoring of Echinococcus multilocularis infection in red foxes in Shiretoko, Japan, by coproantigen detection"Parasitology. 117(2). 193-200 (1998)
NONAKA N.:“通过粪抗原检测来监测日本知床红狐的多房棘球绦虫感染”寄生虫学。
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KONNO K.: "Histopathology and physiopathology of gastric mucouse hyperplasia in rats heavily infected with Taenia taeniaeformis"Journal of Veterinary Medical Science. 61(4). 317-324 (1999)
KONNO K.:“严重感染绦虫带状绦虫的大鼠胃粘膜增生的组织病理学和生理病理学”兽医医学杂志。
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Sakai, H.: "Coproantigen detection in a survey of Echinococcus multilocularis infection among red foxes, Vulpes vulpes schrencki, in Hokkaido, Japan."Journal of Veterinary Medical Science. 60(5). 639-641 (1998)
Sakai, H.:“日本北海道赤狐 (Vulpes vulpes schrencki) 多房棘球绦虫感染调查中的粪抗原检测。”兽医医学杂志。
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SAKAI H.: "Coproantigen detection in a routine fox survey of Echinococcu multilocularis infection in Hokkaido, Japan"Parasitology International. 47(1). 47-51 (1998)
SAKAI H.:“日本北海道多房棘球绦虫感染例行狐狸调查中的粪抗原检测”国际寄生虫学。
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SAKAI H.: "Coproantigen detection in a survey of Echinococcus multilocularis infection among red foxes, Vulpes schrencki, in Hokkaido, Japan"Journal of Veterinary Medical Science. 60(5). 639-641 (1998)
SAKAI H.:“日本北海道赤狐(Vulpes schrencki)多房棘球绦虫感染调查中的粪抗原检测”兽医医学杂志。
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共 34 条
In silico analysis of full-length rich cDNA library of Echinococcus multilocularis, molecular bases of the parasite growth and development, and vaccine
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批准号:20380164
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.31万
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财政年份:2008
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负责人:OKU Yuzaburo
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依托单位:
Control of Echinococcus multilocularis in rural area by anthelminthics application for definitive hosts
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批准号:07557204
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$4.29万
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财政年份:1995
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负责人:OKU Yuzaburo
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依托单位:
Environmental adaptation of Echinococcus in South America
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批准号:06041005
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$10.05万
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财政年份:1994
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负责人:OKU Yuzaburo
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依托单位:
Studies on the host resistance to infection with larval cyclophyllidean cestodes
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批准号:61560331
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.96万
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财政年份:1986
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负责人:OKU Yuzaburo
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依托单位:
海外基金