Facial expression and neural activities in the fronto-opercular cortex during tasting behavior in monkeys

猴子品尝行为期间额叶盖皮层的面部表情和神经活动

• 批准号: 61570069
• 负责人: OGAWA Hisashi
• 金额: $ 1.41万
• 依托单位: Kumamoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1986
• 资助国家: 日本
• 起止时间: 1986 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-61570069/
• 关键词: monkey; fronto-opercular cortex; taste; mechanoreception; mastication; 味覚弁別タスク; 飲水行動; 味覚弁別学習; 下顎部; 筋活動

Neural activities were recorded in the fronto-opercular cortex (Fop) including the gustatory area, of alert monkeys which were conducting tasting behavior. Facial ex-pression of the monkey was also recorded on video-tape, together with neural activities and EMG activities in the masseter. (1) in the Fop of two Japanese monkeys, drinking randomly given fluid from a spout, 3 types of neurons were noticed; On-type neurons re-sponding phasically at the onset of fluid application, Mo-type neurons activated during oral movement, e.g., chewing, and taste neurons differentially activated by different taste solutions. Among the On-type and Mo-type neurons, several tactile neurons with RFs on the lip and/or in the oral cavity were recognized. Though On-type neurons were found at all parts of the Fop, many Mo-type neurons were rather localized at the PrCO and taste neurons at areas G, 1-2 and OFO. (2) Two monkeys were trained to perform GO-NOGO task to discriminate between NaCL (GO cue) and water … More (NOGO cue). Sucrose were used as reward, and quinine as punishment. Reaction time from NaCL infiltration to bar-pressing and % correction ratio were dependent upon NaCL concentration. Neurons in the Fop re-sponded either to both cue stimuli (A-type), one of the cues (B-type), or to sucrose or quinine (C-type). A-type neurons were profound at the PrCO and assumed to be related to the attention in the task performance. B-type were located at areas G, 1-2 and OFO, and considered as taste neurons. C-type neurons were at aresa G, 1-2, and PrCO. Some of them might be related to psychological factor, i.e., reward or punishment, some might be taste neurons. Taste neurons were found in areas G and 1-2 in two types of chronic ex-periments, as in the previous acute experiment using anesthetized monkeys. Neurons in the PrCO may be related to attention in taskperformance. OFO may contained higher-order taste neurons as suggested by Rolls et al. (1985). (3) Gustatory matching to sample task was developed to use a number of taste solutions as cue stimuli to monkeys. Neurons in the Fop of monkeys performing this task will be investigated in near future. Less

记录了进行品尝行为的警觉猴子的额盖皮质(FOP)中的神经活动，包括味觉区。录像还记录了猴子的面部表情，以及咬肌的神经活动和肌电活动。(1)在两只日本猕猴的FOP中，观察到3种类型的神经元：On类型神经元在开始使用液体时反应，Mo型神经元在口腔运动时被激活，不同的味觉溶液不同地激活味觉神经元。在ON型和MO型神经元中，发现有几个触觉神经元在嘴唇和/或口腔内有RFs。虽然在FOP的各个部位都有ON型神经元，但在PRCo和味觉神经元的G区、1-2区和Ofo区有较多的Mo型神经元。(2)训练两只猴子执行Go-NOGO任务，以区分氯化钠(Go Cue)和水…更多(Nogo球杆)。蔗糖作为奖励，奎宁作为惩罚。从入渗到压杆的反应时间和校正百分率取决于盐的浓度。FOP中的神经元对两种线索刺激(A型)、其中一种线索(B型)或蔗糖或奎宁(C型)都有反应。A型神经元在PRCo区分布较深，可能与注意在任务执行中的作用有关。B型分布于G区、1-2区和Ofo区，为味觉神经元。C类神经元分布在G、1-2和PRCo区。其中一些可能与心理因素有关，即奖惩，另一些可能是味觉神经元。在两种类型的慢性实验中，味觉神经元被发现位于G区和1-2区，与先前用麻醉猴子进行的急性实验一样。PRCO中的神经元可能与任务执行中的注意力有关。根据Rolls等人的推测，Ofo可能含有更高级的味觉神经元。(1985年)。(3)以多种味觉溶液作为对猴子的线索刺激，开发了味觉匹配样本任务。在不久的将来，将对执行这项任务的猴子的FOP中的神经元进行研究。较少

项目成果

小川尚: 第20回味と匂のシンポジウム論文集. 129-132 (1986)

小川恒：第 20 届味觉和嗅觉研讨会论文集 129-132（1986）。

H. Ogawa: "Responses of neurons in the frontal operculum of macaque monkeys" Proceedings of the 20th Japanese symposium on taste and olfaction. 129-132 (1986)

H.小川：“猕猴额叶盖神经元的反应”第20届日本味觉和嗅觉研讨会论文集。

小川尚, 伊藤真一: 日本生理学会雑誌. 50. (1988)

小川恒，伊藤新一：日本生理学会杂志 50。（1988）