Synthesis and Production of High Value Pyridines Combining the Concepts of Alternative Reaction Media and Process Intensification

本项目旨在通过汇集绿色化学和过程强化领域的专业知识，开发取代吡啶类化合物的新型合成方法和工艺路线。最大限度地减少废物、提高能源效率以及改善选择性和控制将是生产高价值化合物的关键工艺和化学目标。传统的方法使用有机溶剂和预形成的盐，这些方法成本高，产生废物，并且由于选择性差、产率低和大量的分离步骤，这些方法是能源密集型的。 这是一个通用的调查，将有广泛的应用在制药，能源和先进的电子行业。

This project aims to develop novel syntheses and process route for substituted pyridines by bringing together expertise in the fields of green chemistry and process intensification. Minimisation of waste, energy efficiency, and improved selectivity and control will be the key process and chemistry targets, which will produce high value compounds. Traditional approaches use organic solvents and preformed salts which are costly, generate waste and the processes are energy intensive due to poor selectivity, low yield and extensive separation steps. This is a generic investigation which will have wide ranging applications in the pharmaceutical, energy and advanced electronic industries.