Targeted enzymatic treatment of the injured central nervous system using innovative nanotechnology

利用创新纳米技术对受损中枢神经系统进行靶向酶治疗

• 批准号: DP1094217
• 负责人: Prof Colin Raston AO FAA
• 金额: $ 34.48万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP1094217
• 关键词: Targeted; enzymatic; treatment; injured; central

Nanotechnology and other frontier areas in science have exciting potential to solve major challenges of the 21st century, including health. The proposed research provides the real possibility of discovering ways to alleviate the many complex problems associated with neurotrauma following, for example, brain and spinal cord injury. Current delivery of therapeutics do not work effectively and new approaches are urgently needed. The recently established powerful multidisciplinary research team combines expertise in nanotechnology, glycobiology and neuroscience to develop novel, safe ways to deliver therapeutic enzymes over biological time-courses. We aim to make broken connections work again, while providing quality research training.

纳米技术和其他科学前沿领域在解决包括健康在内的21世纪重大挑战方面具有令人兴奋的潜力。这项拟议的研究提供了真正的可能性，可以找到方法来缓解与脑和脊髓损伤等神经创伤相关的许多复杂问题。目前提供的治疗药物并不有效，迫切需要新的方法。最近成立的强大的多学科研究团队结合了纳米技术、糖生物学和神经科学的专业知识，以开发新颖、安全的方法，在生物过程中提供治疗性酶。我们的目标是让断开的联系重新发挥作用，同时提供高质量的研究培训。