内分泌学研究体制推進の研究ー特に国際協力

促进内分泌研究体系的研究——特别是国际合作

• 批准号: 62308010
• 负责人: 鈴木 光雄
• 金额: $ 1.6万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Co-operative Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-62308010/
• 关键词: アンケート; NIH; ホルモン抗体; RIA; 免疫組織化学; NHPP; 標識ホルモン

内分泌学研究推進のためのアンケート(13項目)を日本内分泌学定評議員, 日本比較内分泌学会々員, 日本生化学会評議員, 日本生理学会評議員, 日本解培学会評議員, 日本組織化学会員あて計2,435通のアンケート用紙を送附した. うち454のアンケート回答が得られた. (回答率:18.64%)アンケート集計の結果は以下のようであった. (1)使用または測定されているホルモンとその類似物質は80種類に及ぶ. (2)使用ホルモンの入手法は66.99が購入, 29.4%が供与を受け3.9%が自家製である. (3)ホルモン測定法は大部分が放射免疫分析法(RIA,87.1%)であった. (4)RIAに用いる標識ホルモンは65.9%が購入により, 自家標識のものは18.5%, 供与されたものは12.8%であった. (5)標識に用いられた放射性同位原素は69.4%が^<125>I,20.5%が3Hで, ^<131>Iは1.7%にすぎなかった. (6)ホルモン抗体の利用法は66%がRIAで, 組識化学の28%がこれに次いだ. (7)ホルモン抗体の入手法は, 26.9%が購入, 45.3が供与, 27.7%自家製であった. (8)標識ホルモンのRIAへの使用量は昭和62年度で1,2234本 過去5年間に4,610千本, 今後5年間で6,330の予定で, 今後37.3%の増加が予想された. (9)一方組織化学に使用される抗体異は切片数として, 昭和62年度に1124枚, 過去5年間に4654枚, 今後5年間に4014枚と13.8%の減少が予想された. (10)また自家製抗体の他研究室への供与のものが34研究室あり, 主回答数の0.75%に及んだ. (11)一方来国NIHの国主ホルモンと下垂体計画(NHPP)から得た資料によると昭和62年度中に同計画から標品の供与を受けたわが国の内分泌研究数は126各に及び, 供与標傾数(バイアル数)として306個であり, 米国に次いでその利用度は世界第2位であることが判った. 以上は内分泌研究の国際協の策定に資するもであると考える.

Endocrinology Research Promotion (13 projects) Member of Japan Endocrinology Research Council, Member of Japan Comparative Endocrinology Society, Member of Japan Biochemical Society, Member of Japan Physiological Society, Member of Japan Society of Anatomy, Member of Japan Histochemistry. 454. (Response rate:18.64%) The results of the survey are as follows: (1)80 species and quantities of similar substances were determined using the method. (2)66.99% of the users were purchased, 29.4% were supplied and received, 3.9% were home-made. (3)Most radioimmunoassay (RIA, 87.1%) is used. (4) RIAs used in the logo, 65.9% of them were purchased, 18.5% of them were owned, and 12.8% of them were supplied. (5)The radioactive isotope used in the identification was 69.4%<125>~ 3H, 20.5%~ 1.7%~ 3H<131>. (6)66% of the antibodies were detected by RIA, and 28% by chemical analysis. (7)26.9% were purchased, 45.3% were supplied, and 27.7% were manufactured. (8)The number of RIA used in the past five years was 4,610 thousand copies, and the number of RIA used in the next five years was 6,330 copies, with an expected increase of 37.3% in the future. (9)The number of antibody sections used in histochemistry was 1124 in 1962, 4654 in the past 5 years and 4014 in the next 5 years, a decrease of 13.8%. (10)The number of responses was 0.75% and 0.75% respectively. (11)The number of endocrine studies conducted by the NIH National Health Programme (NHPP) in 2002 was 126, and the number of studies conducted by the NIH National Health Programme (NHPP) in 2003 was 306. The number of studies conducted by the NIH National Health Programme (NHPP) in 2003 was the second highest in the world. The above is a review of the international co-ordination of endocrine research.