Analysis of quartet lipids in methanogenic bacteria

研究了产甲烷菌热自养甲烷菌中主要四醚类脂质的结构。这些脂质的系统名称为caldarchaeol， gentiobiosyl caldarchaetidyl-X和gentiobiosyl caldarchaetidyl-X （X=乙醇胺，l-丝氨酸和肌醇）。这些脂类分为乙醇胺、丝氨酸和肌醇三组四元组，每组四元组由中性脂、糖脂、磷脂和磷酸糖脂组成。这四组的结构特征为阐明和理解该生物脂质模式的复杂性和生物合成假说提供了有用的线索。通过对二醚极性脂质结构分析的结果，将四重奏概念扩展到七元概念。

The strucutres of major tetraether types of lipids in the methanogen methanobacterium thermoautotrophicum were elucidated. The systematic names of these lipids were caldarchaeol, gentiobiosyl caldarchaeol, caldarchaetidyl-X and gentiobiosyl caldarchaetidyl-X (X=ethanol-amine, L-serine and myo-inositol). These lipids were classifies in three (ethanolamine, serins and inositol) groups of quartets, each of which is composed of neutral lipids, glycolipids, phospolipid and phosphoglycolipid.The structural features of the quartet provided useful clues for elucidation and understanding of the complexity of lipid pattern of this organism and biosynthetic hypothesis. The quartet concept was extended to a heptad concept by the addition of the results of structural analysis of diether polar lipids.