Development of Nd:YAG laser apparatus and vascular endoscopy for laser angioplasty

用于激光血管成形术的 Nd:YAG 激光装置和血管内窥镜的开发

• 批准号: 63440039
• 负责人: TAKEKAWA Shoichi
• 金额: $ 12.22万
• 依托单位: Hirosaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (A)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63440039/
• 关键词: Laser; Laser Angioplasty; Angioplasty; Endoscopy; Vascular endoscopy; Vascular endoscopy; Laser angioplasty; レ-ザ-と温度制御; レーザー装置; レーザー血管拡張術; レーザー血管形成術; LASERANGIOPLASTY; PTLA

1.A newer compact Nd : YAG laser apparatus for laser angioplasty was designed by us and was constructed by Olympus Optical Co. Ltd. The new apparatus is fan-cooled ( no water ), and its maximum power is 50W, which seemed to be sufficient for ordinary use. The apparatus can be controlled by measurement of temperature and computer communication. It was confirmed that the temperature is well controlled at a set temperature and did not exceed significantly the set temperature of a portion of tissue. Measurement of temperature at 2, 4, 6.8 mm from the ceramic tip revealed that the heat produced by laser was very confined to the near vicinity of 2 mm or so.2.According to our specification, a newer narrow vascular endoscope, measuring 1.4 mm in diameter, was developed by Olympus Optical Co. Ltd., of which tip could be bent so that all area in front of the scope could be seen. The new endoscope can be bent at its tip about 22ﾟ. This endoscope increased markedly the visual field. The resolution of the scope was sufficient for clinical use, i.e. recognition of pathology of the arterial wall and aiming the tip of a bare laser fiber.3.The 5-year cumulative patency rates of PTLA for the iliac and femoropopliteal arteries are both about 92%, which seemed to have exceeded the results by conventional PTA.

1.自行设计和奥林巴斯光学有限公司建造的小型新型激光血管成形术装置，该装置为风扇冷却(无水)，最大功率为50W，可以满足日常使用的需要。该装置可通过温度测量和计算机通信进行控制。经证实，温度被很好地控制在设定的温度，并且没有显著超过部分组织的设定温度。在距陶瓷尖端2 mm、4 mm、6.8 mm处的温度测量表明，激光产生的热量非常有限，仅限于2 mm左右。2.根据我们的规范，奥林巴斯光学有限公司开发了一种较新的狭窄血管内窥镜，直径为1.4 mm，其尖端可以弯曲，从而可以看到范围前面的所有区域。这种新型内窥镜的顶端可弯曲约22ﾟ。这种内窥镜明显增加了视野。3.经皮冠状动脉腔内成形术对髂股动脉的5年累积通畅率均约为92%，似乎已超过常规经皮冠状动脉腔内成形术。

项目成果

Miura, M.: "Change in temperature and distribution of heat in the normal arterial wall when laser was irradiated" J. Japan Soc. for Laser medicine, 10:3: 335-338, 1989.

Miura, M.：“激光照射时正常动脉壁的温度和热量分布的变化”J. Japan Soc。

竹川鉦一: "レ-ザ-による血管形成術の臨床" 日本レ-ザ-医学会誌. 10. 19-26 (1989)

Kenichi Takekawa：“激光血管成形术的临床实践”日本激光医学会杂志 10. 19-26 (1989)。

Takekawa,S.: International Nd:YAG Laser Symposium,Los Angeles,California,U.S.A.August. (1988)

Takekawa,S.：国际 Nd:YAG 激光研讨会，美国加利福尼亚州洛杉矶

竹川鉦一: "講演収録集、医療を支える先端技術 第3回「大学と科学」公開シンポジウム組織委員会編" クバプロ, 361 (1989)

Kenichi Takekawa：“讲座集，支持医疗保健的尖端技术，由第三届‘大学与科学’公共研讨会组委会编辑”，Kubapro，361（1989）

竹川鉦一: 日本レーザー医学会誌 特集号. 9. (1989)

Takekawa, Kenichi：日本激光医学会杂志特刊 9。（1989）