Comprehensive Study on the Effective Use of Laboratory Animals which have been Developed and held in Different Institutions

经过两年的合作研究，认为目前在实验动物的信息、质量控制、运输等方面采取以下几种方法是最有利于实验动物在不同机构间的相互利用。(1)数据库的建设和使用。由于大多数机构都安装了由MS-DOS操作的微型计算机，而不是在线操作的计算机系统，因此分发由MS-DOS操作的软盘是使用实验动物数据库最有效的方法。(2)动物的质量控制。ELISA试剂盒检测特异性病原体抗体简便、有效，可用于微生物学质量控制。本研究开发的酶电泳装置简单，可用于大、小鼠遗传质量控制。(3)动物的运输。非冷冻和冷冻胚胎可以在机构之间转移。这些方法有望在未来用于运输动物。

The results of this two-year co-operative research indicate that at the present the following methods on information, quality control, transportation of laboratory animals are best for the mutual utilization of the animals between the different institutions.(1) Construction and use of database. The distribution of diskette which is operated by MS-DOS is the most effective to use the database on the laboratory animals, because most institutions have installed microcomputers which operated by the system but not on-line operated computer system.(2) Quality control of animals. ELISA kit for the detection of the antibodies against the specific pathogens is simple and effective for microbiological quality control. Enzyme electrophoresis by a simple device which developed during this research could be used for genetic quality control of mice and rats.(3) Transportation of animals. Non-frozen and frozen embryos can be transferred between the institutions. The methods are promised future use for the transportation of animals.