Studies on the Scoring System of Diagnosis Using Thermography for Breast Cancer and its Clinical Application
Studies on the Scoring System of Diagnosis Using Thermography for Breast Cancer and its Clinical Application
批准号:
01440051
负责人:
TOGE Tetsuya
金额:
$6.21万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (A)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1990
中文摘要
探讨了热像图在乳腺癌诊断中的作用。应力热成像显示了肿瘤血管对冷却盐水(4 ℃)或血管紧张素II输注的抵抗力。此外,热像表现与淋巴结转移密切相关。肿瘤与对侧温差大于1.5 ℃者预后差。根据病理检查,热像图反映了癌细胞的扩散,虽然热像图的诊断方式不能与乳腺X线摄影或超声相比,但接触式热像图(sinotest)在乳腺癌诊断中的作用与远红外热像图相当。乳腺癌中约有40%左右的乳腺组织出现与对侧温差大于1^0 ℃的高热区,而良性病变中未见,提示乳腺组织的热像表现反映了乳腺组织的代谢和血管现象,不仅可作为乳腺癌的诊断指标,而且可作为乳腺癌普查中高危人群的发现。
英文摘要
The usefulness of thermography in the diagnosis of breast cancer patients was investigated. Stress thermography revealed the resistance of tumor vessels against the infusion of cooled saline (4^0C) or angiotensin-II. Furthermore, thermographical findings closely correlated with lymphnode metastasis. Poor prognosis was found in patients with temperature difference of more 1.5^0C between tumor and contralateral region. According to pathological examination, the hyperthermia area reflected the spread of cancer cells.Although the diagnositic modality of thermography could not compared with that of mammography or ultrasonography, the usefulness of contact thermography (sinotest) in diagnosis of breast cancer was comparable to the tele thermography. Hyperthermic areas with temperature difference of more than 1^0C against contralateral region were found in approximately 40% of nonpalpable breast cancer, while not in benign lesions.These results indicated that thermographic appearance reflect the metabolic and vascular phenomenon in breast tissue and might be useful for not only a prognositic indicator but the detection of high risk group in mass screening.
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Masakazu Toi: "Relationship between epidrmal growth factor receptor status and various prognostic factor in human breast cancer" Cancer. 65. 1980-1984 (1990)
Masakazu Toi:“表皮生长因子受体状态与人类乳腺癌各种预后因素之间的关系”癌症。
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Masakazu Toi: "Immunocytochemical and biochemical analysis of epidermal growth factor receptor expression in human breast cancer tissues : relationship to estrogen receptor and lymphatic invasion" Int. J. Cancer. 43. 220-225 (1989)
Masakazu Toi:“人乳腺癌组织中表皮生长因子受体表达的免疫细胞化学和生化分析:与雌激素受体和淋巴侵袭的关系”Int。
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Masakazu Toi: "Immunocytochemical and biochemical analysis of epidermal growth factor receptor expression in human breast cancer tissues:relationship toestrogen receptor and lymphatic invasion" Int.J.Cancer. 43. 220-225 (1990)
Masakazu Toi:“人乳腺癌组织中表皮生长因子受体表达的免疫细胞化学和生化分析:雌激素受体与淋巴侵袭的关系”Int.J.Cancer。
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戸井 雅和: "腫瘤非触知性乳がんの診断におけるサ-モグラフィ-の有用性" 乳癌の臨床. 4. 238-242 (1989)
Masakazu Toi:“热成像技术在诊断不可触及的乳腺癌中的作用”《乳腺癌临床》,4. 238-242 (1989)。
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黒井 克昌: "早期乳がんの診断に関する臨床的検討" 広島医学.
Katsumasa Kuroi:“早期乳腺癌诊断的临床考虑”广岛医疗。
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共 12 条
A study on overcoming drug resistance by antisense Bcl-2 for breast cancer
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Studies on the enhancement of maxrophage killing by the selective activation of their tumoricidal activity and tumor cell modi-ication
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负责人:TOGE Tetsuya
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依托单位:
海外基金