Experimental study on the effect of Pd-Co dental casting ferro-magnetic alloys in the bone tissue.

Pd-Co牙科铸造铁磁合金对骨组织影响的实验研究。

• 批准号: 63570939
• 负责人: YOSHIDA Yukiko
• 金额: $ 1.28万
• 依托单位: Tokushima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63570939/
• 关键词: implants; Pd-Co dental casting ferro-magnetic alloys; rats; rabbits; bone tissue; histopathology

Many dental implants materials used clinically have been subject to basic investigation. Pd-Co dental casting ferro-magnetic alloys were very useful is a dental material. They were clinically used with good success as a connection of sectional dentures for difficult cases and an attachment of overdentures in combination with the Sm-Co magnets.We studied the bio-compatibility of Pd-Co dental casting ferro-magnetic alloys in vivo by examining their histo-pathological effects on implantation into the intraosseous tissue of rats and rabbits. The experimental periods were from 2 weeks to 3 months. The results were as follows:Though slight inflammations with reddening and swelling were examined at insight for several days after the operation on the surrounding parts of the spiral implants, a few weeks later they healed comparatively rapidly. At the beginning the implanted spiral artificial roots were slightly unsteady, even though treated with fixation by ligation, and after that, they had a tendency to be steadily fixed in the course of days.In the case of 3 months, opaque figures, on account of the bony growth, were observed in the X-ray films from the central part to the edge of the implanted spiral artificial roots. In both of the cases of 2 weeks and 1 months, fibrous connective tissue slightly infiltrated inflammatory cells were seen formed in rings around the metals of implanted spiral artificial roots. The buried metals were surrounded with the dense connective tissues in rings, at the base of which the alveolar bones and the growth of bones were observed. In case of 3 months, at the surrounding of the buried metals the alveolar bones and the growth of bones were observed. Evon though the dental casting ferro-magnetic alloys gave a slight tissue reactions than titanum, few fibrous tissue separation between the implant and bone was obvious.

临床上使用的许多种植体材料都需要进行基础研究。Pd-Co牙科铸造铁磁合金是一种非常有用的牙科材料。它们在临床上作为困难病例的断层义齿连接和覆盖义齿的附着体与钐钴磁体联合使用，取得了良好的成功。通过观察Pd-Co牙铸造铁磁合金在大鼠和家兔骨内植入的组织病理学效果，研究其体内生物相容性。试验期为2周~ 3个月。结果如下：手术后数天内，螺旋种植体周围有轻微的炎症和红肿，但几周后愈合较快。刚开始种植的螺旋人工根即使结扎固定也有轻微的不稳定，之后在几天的时间内有稳定固定的趋势。在3个月的病例中，由于骨生长，x线片从植入的螺旋人工根的中心部分到边缘观察到不透明的图像。在2周和1个月的病例中，可见植入的螺旋人工根金属周围形成纤维结缔组织轻度浸润炎性细胞的环状。埋藏的金属被致密的结缔组织包围成环状，环状底部可见牙槽骨和骨的生长。3个月时，在埋藏金属周围观察牙槽骨及骨的生长情况。虽然铸造铁磁合金比钛有轻微的组织反应，但种植体与骨之间的纤维组织分离很少。