Multichannel Spinal Cord Monitoring System

通过1988~1990年猫的动物实验，研制了一套多通道脊髓监测系统。本课题的基础研究包括以下几个方面：1)脊髓缺血时诱发的脊髓动作点(L2下行ESCP、L5下行ESCP、上升ESCP、节段性ESCP、运动节段性ESCP)与脊髓功能障碍的关系；2)直接测定脊髓血流量的技术问题；3)低温对脊髓动作电位的影响；4)刺激周围神经诱发脊髓电位的起源和传导途径；5)经颅顶-硬腭刺激诱发的运动诱发电位的起源和传导途径；6)硬膜外电刺激对脊髓功能和形态的影响。从这些基础研究的结果中，选择了五个信号来评估脊髓功能障碍。信号由两个特定动作电位的幅度变化、激光系统(动物)检测的脊髓血流量和人体(人体)体温组成。在该报警系统中，这些数据被输入到计算机系统中，并自动显示为带有参考的雷达图。该系统被认为能够检测到脊髓的缺血变化以及机械损伤。该系统由硬件和软件组成，可用于动物脊髓手术或主动脉手术中脊髓功能障碍的检测。

A multichannel spinal cord monitoring system has been developed through the animal experiments using cats from 1988 to 1990. The basic study in thisproject consisted of the following researches : 1) Relationships between evoked spinal cord action pot entials (L2 descending ESCP, L5 descend ESCP, ascemndng ESCP, segmental ESCP, and motor segmental ESCP) in spinal cord ischemia and the cord dysfunction, 2) Technical problems on deliveration of direct determination of spinal cord blood flow, 3) Effects of hypothermia on spinal cord action potentials, 4) Origins and conducting tracts of evoked spinal cord potentials elicited by peripheral nerve stimulation, 5) Origins and conducting pathways of motor evoked potentials elicited by transcranial (vertex-hard palate) stimulation, and 6) Effects of epidural electrical stimulation modalities on spinal cord function and morphlogy. From the results of these basic researches, five signals were selected for evaluation of spinal cord dysfunction. The signals were consisted of amplitude changes of the two definite action potentials, spinal cord blood flow detected by laser system (in animals), and body temperature (in human). In this alarm system, these datas were put in a computer system, and automatically displayed as a radar chart with the reference. This system is thought to be able to detect the ischmic changes as well as the mechanical insults to the cord. This system composed of hard and soft wares, and the availability was confirmed for detecting cord dysfunctions during spinal cord surgery or aortic surgery in animals.