Development of a computation system to calculate temperature distribution for hyperthermic treatment

温度决定了患者对热疗的反应，了解患者的温度分布是有效实施热疗和评估热疗效果的必要条件。研制了一种计算病人体温分布的系统。它由一台16位个人电脑和一个40MB的硬盘组成，并计算用射频电容加热装置加热的病人的二维温度分布。用有限元法计算了CT数据的稳态和非稳态温度分布。CT数据输入后约10分钟即可得到稳态温度分布。非稳态温度分布计算所需的时间等于治疗患者所需的时间。虽然定量评估仍然存在问题，但该系统为临床治疗提供了有用的信息。通过与计算机中心的电话连接，使用计算三维温度的计算机程序和考虑治疗过程中血流量变化的非线性计算机程序。然而，该系统被认为不适合在医院使用，因为它需要太多的时间来传输数据，并且系统的维护困难。一种可用于组织循环研究的系统已经开始研制。我们研究了几种计算机程序，但对用于计算温度分布的参数知之甚少。热疗期间的血流量已经做了很多工作，热扩散法是一种实用的方法，通过热疗期间获得的冲洗曲线来测量血流量。然而，对其他参数的研究很少。研制了一种可用于医院的热模型原型。一旦我们熟悉了它，我们就可以为改进系统提供基础数据，使定量估计成为可能。少

Temperature determines responses to hyperthermic treatment, and knowledge of the temperature distribution in a patient is required for carrying out such treatment efficiently and for assessing its efficiency. A system to calculate temperature distribution in a patient was developed. It consists of a 16-bit personal computer and a 40MB hard disk and Calculates a two-dimensional temperature distributibn in a patient heated with a RF capacitive heating unit. Both steady state and non-steady state temperature distributions were calculated from CT data by using a finite element method. A steady state temperature distribution could be obtained in about 10 minutes after the input of the CT data. A non-steady state temperature distribution calculation took an amount of time equal to that needed to treat the patient. Although quantitative evaluation remains problematic, the system provides imformation useful for clinical tratment. The computer programs for calculating three-dimensional temperat … More ure distribution and non-linear computer programs which consider changes in blbod flow during treatment were used via telephone connection to a computer center. Howevdr, this system was regarded as unsuitable for use at hospitals because it took toomuch time for data transfer and maintenance of the system was difficult. Development has begun on a system which can be used in research on tissue circulation. We investigated several kinds of computer programs but had lottle information about the parameters used for calculation of temperature distribution. Much work has been done on blood flow during hyperthermia, and the thermal diffusion method, which measures blood flow from washout curves obtained during hyperthermic treatment, was found to be practical method. However, little investigation has been done on other parameters. A prototype of thermal modeling was developed which could be used at hospitals. Once we become familiar with it, we can offer fundamental data for improving the system to a stage where quantitative estimation is possible. Less