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The Ultrasonic physiotherapy for Prostatic Diseases

超声波理疗治疗前列腺疾病

基本信息

批准号：
01570906
负责人：
ISHIBASHI Akira
金额：
$ 1.41万
依托单位：
Kitasato University School of Medicine
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1989
资助国家：
日本
起止时间：
1989 至 1991
项目状态：
已结题

项目摘要

In 1975, Karpukin and his associates of former Soviet Union have developed transrectal ultrasonic applicator which has been used for physiotherapy to chronic, nonspecific prostatitis. At that time they applied hydrocortisone acetate ointment ultrasonic applicator.Their successful and unique therapeutic modality to clonic prostatitis has been followed by our study, although we emploed this modality for treating benign prostatic hypertroply (BPH).In the era of an aging society, the development of a new strategy for the conservative treatment of bening prostatic hypertrophy (BPH) has long been anticipated.This prospdctive study was an effort to evaluate the effectiveness of transrectal ultra-sonic physiotherapy (TRUP) for the symptomatic relief of BPH. Patients were treated with ultrasound beam irradiated from a transrectally placed applicator which was developed in the former Soviet Union.The interval and intensity of the pulsed-ultrasound were 10 msec and 0.4 W/cm^2, respectively. The treatment was performed once a day for 7 consecutive days.Improvements in symptom scores and objective parameters were observed in approximately 40% of the first 25 cases in the pilot trial. In the second trial, symptomatic relief was also obtained in approximately 40% of 115 ptients.Patients who needed surgical intervention after 6months of TRUP showed a much higher incidence of aggravation in their obstructive symotoms (70%) than. other groups. On the other hand symptords improved with time after TURP in 17% of the 42 patients who were followed without any other therapy.We conclude that TRUP is an effective conservative treatment for BPH with. few side effects. Further investigation is warranted.

1975年，前苏联的卡尔普金和他的同事开发了经直肠超声治疗仪，用于慢性非特异性前列腺炎的物理治疗。当时他们使用的是醋酸氢化可的松软膏超声治疗仪。他们对阵挛性前列腺炎的成功而独特的治疗方式一直被我们的研究所效仿，尽管我们用这种方式治疗良性前列腺肥大（BPH）。在老龄化社会时代，人们早就期待制定一种新的治疗良性前列腺肥大（BPH）的策略。前瞻性研究旨在评估经直肠超声物理治疗 (TRUP) 对缓解 BPH 症状的有效性。患者接受前苏联开发的经直肠放置的超声治疗仪照射的超声波束进行治疗。脉冲超声的间隔和强度分别为10毫秒和0.4 W/cm^2。治疗每天进行一次，连续 7 天。在试点试验的前 25 个病例中，大约 40% 的患者观察到症状评分和客观参数的改善。在第二项试验中，115 名患者中约 40% 的症状也得到缓解。接受 TRUP 6 个月后需要手术干预的患者的阻塞性症状加重发生率 (70%) 明显高于其他患者。其他团体。另一方面，在未进行任何其他治疗的 42 名患者中，17% 的症状随 TURP 时间的推移而改善。我们得出结论，TRUP 是治疗 BPH 的有效保守治疗方法。副作用很少。需要进一步调查。