The Quantitative Elucidation of the Correlation Between Bone Growth and Masticatory Function.

骨生长与咀嚼功能之间相关性的定量阐明。

• 批准号: 01571128
• 负责人: HIRAIDE Takatoshi
• 金额: $ 1.28万
• 依托单位: Showa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1989
• 资助国家: 日本
• 起止时间: 1989 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-01571128/
• 关键词: soft foods; masticatory muscle; muscle-fiber type; ATPase staining method; mandible

The purpose of this study was to elucidate the influence of histochemical characteristic of masticatory muscle-fibers on craniofacial growth in rats.One group fed a normal hardness food as a control (group A), while another three groups (group B-D) fed a soft diet in order to induce a low functional activity. Group B was less loaded than group A, group C was powder, and group D was our own making.The experimental period was 29 weeks and started from 3-week-old rats.(Results) 1. Body weight was decreased in group C till the end of 4th weeks of the experimental period. 2. Decrease in linear measurement of mandibular length was found only in group C and decreasing linear measurement of mandibular height was found in group C and group D.Comparing group A with group D by ATPase staining method gave attention of the histochemical characteristic of muscle-fibers in masseter and temporalis muscles. It showed changes of fibers area composition and decrease of fiber diameter.The most important finding was the correlation between the most affected period of mandibular vertical growth and most affected period of changes of masseter and temporalis muscles.Changing in the histochemical characteristic of muscle-fibers loading on the mandible was suggested to suppress mandibular vertical growth.

为探讨咀嚼肌纤维组织化学特征对大鼠颅面生长发育的影响，一组大鼠喂正常硬度食物（A组），另三组大鼠喂软食（B-D组），以诱导低功能活动。B组为低负荷组，C组为粉末组，D组为自制组，实验期为29周，从3周龄开始。（结果）1. C组体重下降至实验第4周末。2.仅C组下颌骨长度线性测量值减少，C组和D组下颌骨高度线性测量值减少。通过ATP酶染色法比较A组和D组，注意咬肌和颞肌肌纤维的组织化学特征。结果表明，下颌骨垂直生长最受影响的时期与咬肌和颞肌变化最受影响的时期之间存在相关性，提示下颌骨负荷肌纤维组织化学特征的变化抑制了下颌骨的垂直生长。