Studies on the effect of wheat gluten diets in pregnant rats and improvement of its nutritional effect

研究了谷朊粉日粮对孕鼠分娩和子代生长的影响及赖氨酸对谷朊粉日粮的补充作用。妊娠大鼠分别饲喂蛋白质水平为5%（G5）、10%（G10）、20%（G20）和30%（G30）的谷朊粉日粮，以及添加0.4%（G5+L）、0.5%（G10+L）、0.8%（G20+L）和1.0%（G30+L）的L赖氨酸日粮。对照组为10%蛋白质饲料的纯化全蛋蛋白。各组大鼠在哺乳期均转为正常饲料喂养，但G5、G5+L和G10组大鼠均能妊娠分娩，但仍有部分大鼠出现新生儿死亡和生长发育迟缓。G5组和G5+L组子代哺乳期死亡率高于对照组。添加10%和20%赖氨酸的小麦蛋白日粮组，赖氨酸的补充效果显著。与对照组相比，饲喂含赖氨酸的20%或30%小麦蛋白饲料以及30%小麦蛋白饲料的组的新生仔鼠表现出几乎相同的生长。妊娠期蛋白质缺乏引起的新生仔鼠生长迟缓，哺乳期正常饮食可恢复。在出生后21天，饲喂含赖氨酸的10%小麦蛋白饲料组和饲喂20%小麦蛋白饲料组的后代与对照组的后代相比，生长几乎相同。

Influence of wheat gluten diets for pregnant rats on the maternal delivery and the growth of the progeny and supplementary effects of lysine to wheat gluten diets studied. Pregnant rats were fed on wheat gluten diets at protein level of 5%(G5), 10%(G10),20%(G20) and 30%(G30), and also the diets added with L lysine at level of 0.4%(G5+L), 0.5%(G10+L), 0.8%(G20+L), and 1.0%(G30+L), respectively. Control was set at 10% protein diet of purified whole egg protein. Every group of diet was converted to normal one during lactation.Although all groups of pregnant rats fed on the wheat gluten diets performed pregnancy and delivery, some in the groups of G5, G5+L and G10 showed neonatal death and stunted growth. The mortality rate of the progeny in G5 and G5+L groups during the period of lactation was higher than that of the control group. Supplementary effects of lysine were significantly observed in the groups fed on 10% or 20% wheat protein diets with lysine. Newborn pups of groups fed on 20% or 30% wheat protein diets with lysine and also on 30% wheat protein diet showed almost the same growth compared with the rats of the control group. The growth retardation of newborn pups caused by deficiency of protein during pregnancy can be recovered by normal diet during lactation. The progeny of groups fed on 10% wheat protein diets with lysine and also on 20% wheat protein diet showed almost the same growth compared with the progeny of the control group at 21st day after birth.