Developmental research of a new 1020-site optical recording system for monitoring neural activity of central nervous system.

用于监测中枢神经系统神经活动的新型1020点光学记录系统的开发研究。

• 批准号: 03557006
• 负责人: KAMINO Kohtaro
• 金额: $ 11.07万
• 依托单位: Tokyo Medical and Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B)
• 财政年份: 1991
• 资助国家: 日本
• 起止时间: 1991 至 1993
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03557006/
• 关键词: central nervous system; neural activity; optical recording; 1020-site optical recording system; ニュ-ロン活動

We have constructed a new 1020-site optical system for simultaneous recording of transmenbrane electrical activity, using a 34 x 34-element photodiode array. This new apparatus permits analysis of the spatio-temporal patterning of neural activity, such as action potentials and postsynaptic potentials, in the central nervous system, at higher spatial and temposal resolutions.

我们已经建立了一个新的1020位的光学系统，同时记录跨膜电活动，使用34 × 34元件的光电二极管阵列。这种新的仪器允许分析的时空模式的神经活动，如动作电位和突触后电位，在中枢神经系统中，在更高的空间和时间分辨率。

项目成果

Sakai, T., Komuro, H., Katoh, T., Sasaki, H., Momose-Sato, Y.and Kamino, K.: "Optical detemination of impulse conduction velocity during development of the embryonic chick cervical vagues nerve bundle." Journal of Physiology (London). 439. 361-381 (1991)

Sakai, T.、Komoro, H.、Katoh, T.、Sasaki, H.、Momose-Sato, Y. 和 Kamino, K.：“胚胎鸡颈模糊神经束发育过程中冲动传导速度的光学测定。

Sato, K., Momose-Sato, Y., Sakai, T., Hirota, A.and Kamino, K.: "Optical multiple-site/sectioning recording assessment of neural response areas to glosspharyngel stimulus in the early embryonic chick brainstem." Journal of Neuroscience. in press.

Sato, K.、Momose-Sato, Y.、Sakai, T.、Hirota, A. 和 Kamino, K.：“光学多位点/切片记录评估早期胚胎鸡脑干中舌咽刺激的神经反应区域。

Sato,K.: "Optical assessment of spatial patterning of strength-duration relationship for vagal responses in the early embryonic chick brainstem." Japanese Journal of Physiology. 43. 521-539 (1993)

Sato,K.：“对早期胚胎鸡脑干迷走神经反应的强度-持续时间关系的空间模式进行光学评估。”

Momose-Sato,Y.: "Optical mapping of the early development of the response pattern to vagal stimulation in embryonic chick brain stem." Journal of Physiology(London). 442. 649-669 (1991)

Momose-Sato,Y.：“胚胎鸡脑干迷走神经刺激反应模式早期发育的光学绘图。”

H。Komuro: "Optical monitoring of early appearance of spontaneous membrane potential changes in the embryonic chick medulla oblongata using a voltage-sensitive dye." Neuroscience. 52. 55-62 (1993)

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