Development of a PET-measuring system for the monkey brain.

当两只恒河猴正在进行简单的视觉反应石灰任务和具有对称加强的视觉引导进行/不进行任务时，进行了PET测量。完成了让猴子坐在灵长类座椅上执行学习任务并收集0-15水局部血流活动变化数据的系统。还完成了两只尼氏染色猴子大脑的连续组织学切片。因此，成功地进行了任务执行过程中局部血流量的检测，并使激活区域的细胞结构识别成为可能。在视觉反应时间任务中，除了对侧手部运动区的常规区域激活外，双侧运动关联区(6区)和对侧46区也被激活。在GO/NO-GO任务中，彩色线索刺激引起了颞下皮质(22区)、内嗅觉中枢和海马-副海马回的激活，提示它们被激活以记忆颜色和随后的操作，而对侧运动区、8区和PreSMA被激活，表明它们被激活以选择GO或NO-GO操作。

While two rhesus monkeys were performing a simple visual reaction Lime task and a visually guided GO/NO-GO task with symmetrical reinforcement, a PET measurement was performed. Systems to let the monkey, sitting in a primate chair, perform the learned task and collect data of activity changes of the local blood flow with 0-15 water were completed. Continuous histology sections of the brain of two monkeys with Nissl stains were also completed. Therefore, mcasuremenltof the local blood flow during the task performance were successfully conducted and cytoarchitectural identifications of activated areas became possible. During a visual reaction time task, in addition to the conventional areal acrivation of the contralateral hand motor area, bilateral motor association areas (areas 6), and contralateral area 46 were activated. During a GO/NO-GO task, colored cue stimuli induced activations of the inferotemporal cortex (area 22) and entorhinal certex and hippocampal-parahipocampal gyri, suggesting their activation to remember the color and succeeding performance, and activation of the contralateral motor area, area 8 and preSMA,indicating their activations for selection of the GO or NO-GO performance.