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Development of Implantable Electrode for Functional Electrical Stimulation.

用于功能性电刺激的植入式电极的开发。

基本信息

批准号：
06555197
负责人：
IGUCHI Yasutaka
金额：
$ 7.1万
依托单位：
TOHOKU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1996
项目状态：
已结题

项目摘要

The functional electrical stimulation (FES) system is very effective in order to restore motor functions of the paralyzed extremities in spinal cord injury and carebral disease patients. The applicants have been developed as stimulator with percutaneous intramuscular electrodes and have been utilizing clinically the system. However, this system has unavoidable problems such as infection and breakage at the position where electrodes go through skin, careful daily maintenance, and cosmetically unfavorable upon patients. Therefore, development of a totally implanted FES system is necessary. In this study more reliable electrodes have been developed than the present percutaneous electrodes. The obtained results are as follows :1. Chromium-cobalt alloy was refined by electro-slag remelting and 25 mum diameter wire was drawn as well as SUS316L stainless steel. The mechanical properties were well satisfied.2. Pitting corrosion was observed on the SUS316L wire in saline solution with accelerated corrosion test by applying electric current, on the contrary, no pitting corrosion on the 604PH wire.3. In order to easily and stably connect electrodes with the stimulator during operation, design of connectors and electrode tip were developed.4. Prototype systems of totally implanted FES with the electrodes of two kinds of materials (SUS316L and 604PH) were implanted in sheep and operating check of the system has been carried out. Useful information has been expected for development of the final system.

功能性电刺激（FES）系统是恢复脊髓损伤和脑血管病患者瘫痪肢体运动功能的有效方法。申请人已开发为具有经皮肌内电极的刺激器，并已在临床上使用该系统。然而，该系统具有不可避免的问题，诸如在电极穿过皮肤的位置处的感染和破损、日常维护的细致以及对患者不利的美容。因此，研制完全植入式FES系统是必要的。在这项研究中，已经开发出比目前的经皮电极更可靠的电极。主要研究结果如下：1.通过电渣重熔精炼铬-钴合金，并将25 μ m直径的线材与SUS 316L不锈钢一样拉拔。力学性能良好.在盐水溶液中，通过加电流加速腐蚀试验，SUS 316L钢丝出现点蚀，而604 PH钢丝没有出现点蚀.为了使手术过程中电极与刺激器的连接方便、稳定，对连接器和电极头端进行了设计.将SUS 316L和604 PH两种材料电极的全植入式FES原型系统植入绵羊体内，并进行了系统的运行检查。期望为最终系统的开发提供有用的信息。