Development and Evaluation of Alloys for the Electrodes for Functional Electrical Stimulation to Appropriate for the Long Term Implantation

适合长期植入的功能性电刺激电极合金的开发和评估

• 批准号: 10450251
• 负责人: IGUCHI Yasutaka
• 金额: $ 5.06万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-10450251/
• 关键词: FES; Electrode; Stainless Steel; Fatigue; Elution; Nickel; Manganese; Nitrogen; 機能的電気刺激; 生体材料; インプラント材料; 機能再建; 疲労特性; 疲労試験; 腐食; 磁性

Alloys for the electrodes for FES(Functional Electrical Stimulation)were developped and evaluated to appropriate for thelLong term implantation. And following results were obtained.1. Development of New Alloy : A database for alloy designing was created. And ingots of some high-manganese high-nitrogen austenitic stainless steels were producted experimentaly. Relation between reduction and elongation or reduction of area of these alloys were tested. And, it was confirmed that the alloy named NAS106N(6mass%Mn, 10mass%Ni, 22mass%Cr, 2mass%Mo, 0.4mass%N)shows the most superior properties. And thin wire rope for FES electrodes were made by this alloy.2. Evaluation of FES Electrodes made by New Alloy : Magunetization curves of FES wires made by newly developed alloy NAS106N, stainless steell SUS316L and cobalt-chromium based alloy NAS604PH were measured. NAS106N and NAS604PH shows the superior non-magnetic properties than SUS316L, Fatigue life of electrodes made by NAS106N, NAS605PH, SUS316L in air and 0.9%NaCl saline solution were also measured by dual-driven rotating-bending test. NAS106N has higher fatigue life than SUS316L and NAS604PH at all experimental condition in air and high at stress conditions in saline solution. On the other hand, fatigue lives of SUS316L and NAS106 were lower than NAS604PH at low stress condition in saline solution.Accordingly, NAS106N will be promising material for FES electrodes but to prevent the fretting corrosion should be the problem to be solved.

用于功能性电刺激(FES)电极的合金被开发并评估为适合于长期植入。并取得了以下结果：1.新合金的开发：建立了合金设计数据库。并试制了一些高锰高氮奥氏体不锈钢铸锭。测试了这些合金的压下率与延伸率或面积缩小率之间的关系。并确定了NAS106N合金(6质量%Mn、10质量%Ni、22质量%Cr、2 MASS%Mo、0.4质量%N)具有最优的性能。用该合金制作了FeS电极用细钢丝绳。新合金制造的FeS电极的评价：测量了新开发的合金NAS106N、不锈钢SUS316L和钴铬基合金NAS604PH制造的FeS电极的磁化曲线。NAS106N和NAS604PH的非磁性性能优于SUS316L，并采用双驱动旋转弯曲试验对NAS106N、NAS605PH、SUS316L制作的电极在空气和0.9%氯化钠盐水溶液中的疲劳寿命进行了测试。在所有实验条件下，NAS106N在空气中的疲劳寿命均高于SUS316L和NAS604PH，在盐水中的应力条件下，NAS106N的疲劳寿命较高。另一方面，在低应力条件下，SUS316L和NAS106的疲劳寿命低于NAS604PH，因此，NAS106N有望成为FeS电极材料，但防止微动腐蚀是亟待解决的问题。

项目成果

M.Watanabe, T.Narushima, T.Kinami, Y.Iguchi, N.Hoshimiya and Y.Handa: "Evaluation of Fatigue Properties of High Nitrogen High Manganese Austenitic Stainless Steel as an FES Electrode"IFESS'99PROCEEDINGS, 4th Annual Conference of the Intrnational Functinal

M.Watanabe、T.Narushima、T.Kinami、Y.Iguchi、N.Hoshimiya 和 Y.Handa：“作为 FES 电极的高氮高锰奥氏体不锈钢的疲劳性能评估”IFESS99PROCEEDINGS，第四届年会

Y.Iguchi: "Investigation of the used FES electrodes and development of new electrode for totally implanted FES system"Proceedings of the 8th Korea-Japan FES Symposium. 4-4 (1998)

Y.Iguchi：《已用FES电极的研究和全植入FES系统新电极的开发》第八届韩日FES研讨会论文集。

M.Watanabe,T.Narushima,T.Kinami,Y.Iguchi,N.Hoshimiya and Y.Handa: "Evaluation of Fatigue Properties of High Nitrogen High Manganese Austenitic Stainless Steel as an FES Electrode"IFESS'99 PROCEEDINGS,4th Annual Conference of the International Functional E

M.Watanabe、T.Narushima、T.Kinami、Y.Iguchi、N.Hoshimiya 和 Y.Handa：“作为 FES 电极的高氮高锰奥氏体不锈钢的疲劳性能评估”IFESS99 论文集，第四届年会

Yasutaka Iguchi,Takayuki Narushima,Masatoshi Watanabe,Tsunetoshi Kinami,Yasunobu Handa and Nozomu Hoshimiya: "Investigation of the used FES Electrodes and Development of New Electrode for totally implanted FES System" Proceedings of the 8th Korea-Japan FE

Yasutaka Iguchi、Takayuki Narushima、Masatoshi Watanabe、Ttsunetoshi Kinami、Yasunobu Handa 和 Nozomu Hoshimiya：“使用过的 FES 电极的调查和用于完全植入 FES 系统的新电极的开发”第八届韩日 FE 会议论文集

Y.Iguchi, T.Narushima, M.Watanabe, T.Kinami, N.Hoshimiya and Y.Handa: "Collaboration and Technology Transfer Between Universities and Industries on Development of Electrodes as the Interface for FES(Functional Electrical Stimulation)"Proceedings of the In

Y.Iguchi、T.Narushima、M.Watanabe、T.Kinami、N.Hoshimiya 和 Y.Handa：“大学和工业界在开发电极作为 FES（功能性电刺激）接口方面的合作和技术转让”论文集