Co-operative Research on Clinical Application and Functional Preservation of Heart and Heart-lung Transplantation
Co-operative Research on Clinical Application and Functional Preservation of Heart and Heart-lung Transplantation
批准号:
07307015
负责人:
NAKAJIMA Jun
金额:
$15.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1997
中文摘要
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英文摘要
Kaihara investigated information Network System for multi organ sharing and more appropriate to implement required features than a classical main frame, especially the details about handling informations on inter net system. Matsuda investigated graft coronary atherosclerosis is preset in the first several days of transplantation. Tabayashi and Isobe reported ACE inhibitor, Angiotensin II receptor antagonist, cell cycle gene decoy and anti adhesion molecule prevent graft atherosclerosis. Sano investigated the donor heart Function harvested after 1 hour of warm cardiac arrest. Taira reported feasibility of hyaluronidase fo rtified cardioplegia. Koyanagi studied new immunosuppressive agent. Kawashima and Nakatani reported two endostage cardiomyopathy cases. They were successfully treated with left ventricular assist device and still alive after weaning of the device. Furuse, Takamoto, Nakajima investigated discordant xenoheart transplantation in infantile monkeys. Hujimura, Eguchi, Yada experimentally investigated lung preservation and immunosuppressive therapy.
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Sawa Y et al: "A norel strategy for myocardial protection using in vivo franefection of cis element ,'Decoy'against NFKB Binding Site" Circulation. 96. II-280-II-285 (1997)
Sawa Y 等人:“Norel 策略利用体内顺式元件‘诱饵’对抗 NFKB 结合位点进行心肌保护”循环。
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Isobe M et al: "Acceptance of primary skin graft after treatment with anti intercellular adhesion molecule-1 and anti-leucocyte function associated antigen 1 monoclonal antibodies in mice" Transplantation. 62. 411-413 (1996)
Isobe M 等人:“小鼠用抗细胞间粘附分子 1 和抗白细胞功能相关抗原 1 单克隆抗体治疗后接受原代皮肤移植” 移植。
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Suzuki J et al: "Prevention of graft coronary atherosclerosis by antisense cdk2 kinase oligonucleotide" Nature Medicine. 3. 900-903 (1997)
Suzuki J 等人:“通过反义 cdk2 激酶寡核苷酸预防移植冠状动脉粥样硬化”《自然医学》。
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Sawa Y et al: "Efficient gene transfer method into the whole heart through the coronary artery with hemagglutinating virus of Japanese liposime" J.Thorac.Cardiovasc.Surg.113(3). 512-519 (1997)
Sawa Y等人:“使用日本脂质体的血凝病毒通过冠状动脉将基因有效转移到整个心脏的方法”J.Thorac.Cardiovasc.Surg.113(3)。
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Isobe M et al: "Acceptance of primary skin graft after treatment with anti-intercellular adhesion molocule-1 and anti-leucscyte function-associated antigen-1 monoclonal antibadies in mice" Transplantation. 62(3). 411-413 (1996)
Isobe M 等人:“在小鼠中用抗细胞间粘附分子 1 和抗白细胞功能相关抗原 1 单克隆抗体治疗后接受原代皮肤移植” 移植。
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