Assessment of Gastric Motor Function by Cine Magnetic Resonance Imaging

电影磁共振成像评估胃运动功能

• 批准号: 18591480
• 负责人: NAKAJIMA Jun
• 金额: $ 1.79万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18591480/
• 关键词: MRI; gastric motility; gastric emptying; mosapride citrate; pylorus-preserving gastrectomy; 幽門保存胃切除術; 幽門輪温存膵頭十二指腸切除術; cineMRI; cine MRI; 胃蠕動運動

Background and Goals: The aim of this study was to evaluate the gastric motor function by magnetic resonance imaging (MRI), and it investigated whether this examination is a useful tool for therapeutic efficacy or postoperative gastric motor function.Methods: Twenty-five healthy volunteers and 10 gastric cancer patients with pylorus-preserving gastrectomy (PPG) underwent cine-MRIs. Gastric volume was determined by 3D-volumetry. Gastric motility was quantified by calculating the gastric motility index (GMI).Results: The image acquisition and analysis were successfully performed for all subjects. In healthy volunteers, the mean frequency, amplitude, velocity of gastric peristaltic waves, and GMI 30 minutes after the intake of jelly were 3/min, 8.8mm, 2.2mm/s, and 19.6mm2/s, respectively. The mean amplitude (8.8 vs. 10.4 mm, p=0.027), velocity (2.2 vs.2.6 mm/s, p<0.001) of peristaltic waves, GMI (19.6 vs.26.7 mm2/s, p<0.001), and gastric emptying rate (18.2vs.27.5%, p=0.004) significantly increased at 30 minutes after mosapride citrate administration. PPG patients with postprandial symptoms were observed having antiperistalsis-like contraction waves and reflux of gastric contents from the pyloric region into the upper part of the stomach. The mean gastric emptying rate in PPG patients with postprandial symptoms at 30 minutes after the intake of jelly tended to be less than in those without such symptoms(9.9vs.22.1%).Conclusions: The present study demonstrates that cine-MRI is a sensitive and noninvasive imaging technique for simultaneously measuring gastric motility and emptying.

背景和目标：本研究的目的是通过磁共振成像（MRI）评价胃运动功能，并探讨此检查是否是一个有用的工具，治疗效果或术后胃运动functions.Methods：25名健康志愿者和10例胃癌患者的幽门保留胃切除术（PPG）进行电影MRI。胃容量测定采用三维容积法。结果：所有受试者均成功完成了图像采集和分析。健康志愿者胃蠕动波的平均频率、振幅、速度和GMI分别为3次/min、8.8mm、2.2mm/s和19.6mm ~ 2/s。枸橼酸莫沙必利给药后30分钟，蠕动波的平均振幅（8.8 vs. 10.4 mm，p=0.027）、速度（2.2 vs.2.6 mm/s，p <0.001）、GMI（19.6 vs.26.7 mm 2/s，p<0.001）和胃排空率（18.2 vs.27.5%，p=0.004）显著增加。观察到有餐后症状的PPG患者具有抗水肿样收缩波和胃内容物从幽门区反流到胃上部。PPG患者在摄入果冻后30分钟有餐后症状的平均胃排空率倾向于低于那些没有这种症状（9.9vs.22.1%）。结论：本研究表明，电影MRI是一种敏感和非侵入性的成像技术，同时测量胃动力和排空。

项目成果

Cine MR画像による胃運動機能評価の試み

尝试使用 Cine MR 图像评估胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤
• 通讯作者: 中嶋 潤

Cine MRイメージを用いた術後胃運動機能の評価

使用 Cine MR 图像评估术后胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤;Jun Nakajima;中嶋 潤;中嶋 潤
• 通讯作者: 中嶋 潤

Cine Magnetic Resonance Imaging for Assessment of Gastric Motor Function after Gastrectomy

电影磁共振成像评估胃切除术后胃运动功能

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba;中嶋 潤;Jun Nakajima;中嶋 潤;中嶋 潤;Jun Nakajima
• 通讯作者: Jun Nakajima

消化器外科術後の胃運動機能評価としてのcine MRIの可能性について

电影 MRI 评估胃肠手术后胃运动功能的可能性

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗
• 通讯作者: 馬場誠朗

Usefulness of Cine Magnetic Resonance Imaging for the Assessment of Gastric Motor Function after Gastrectomy

电影磁共振成像在评估胃切除术后胃运动功能中的作用

• 发表时间: 2007
• 作者: 伊佐地秀司;加藤宏之;ほか;伊佐地秀司(分担);伊佐地秀司(分担);馬場誠朗;Shigeaki Baba
• 通讯作者: Shigeaki Baba