Development of Treatment Planning for High Dose Rate Brachytherapy using 3D-Simulation Model
Development of Treatment Planning for High Dose Rate Brachytherapy using 3D-Simulation Model
批准号:
07407027
负责人:
INOUE Toshihiko
金额:
$1.22万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1996
中文摘要
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英文摘要
3D-simulation model is made from the 3D image of CT or MRI using milling machine. 3D milling machine named ENDOPLAN was installed in 1993, and was applied for brachytherapy. There were no trial of the 3D model for brachytherapy around the world.The aim of this research is to develop the treatment planning and precise treatment technique using 3D simulation model. To deliver the high dose to the tumor, applicators for the guide of the sealed radioisotopes must be placed in the appropriate or planned position. It is easy to insert or place the applicators in the appropriate position using 3D-simulation model.To avoid the high dose for the critical organs, a spacer was placed between the applicators and the critical organs. It was easy to make an appropriate shape of spacer using the 3D-simulation model.Treatment results of the brachytherapy were influenced by the technique and experience of doctors in charge. However, using 3D-simulation model, doctors can easily obtain appropriate arrangements of the applicators and appropriate dose distribution. This precise treatment planning and technique will make the next step of the brachytherapy. Our clinical study of the high dose rate brachythrapy for malignant tumor is the leading study the world, and treatment planning using 3D-simulation model is also only unique study in the world.We are making a plan to use both of the 3D-simulation model and 3D imaging to obtain an appropriate arrangement of the applicators and dose distribution which dose not need the long clinical experience of doctors for the brachytherapy.
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Yamazaki,H.,Inoue To.: "High dose rate brachytherapy using a template technique for pelvic malignanci" Endocurietherapy Hyperthermia Oncology. 12. 145-152 (1996)
Yamazaki,H.,Inoue To.:“使用模板技术治疗盆腔恶性肿瘤的高剂量率近距离放射治疗”Endocurietherapy Hyperthermia Oncology。
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小泉雅彦,井上俊彦: "3次元実体モデルを応用した小線源治療計画" 日本医学放射線学会誌. 55(8). 603-605 (1995)
Masahiko Koizumi、Toshihiko Inoue:“使用三维物理模型进行近距离治疗规划”日本医学放射学会杂志 55(8) 603-605 (1995)。
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Shimizutani,K.,Inoue To.: "Application of ^<198>Au grains for carcinoma of oral cavity." Strahlentherpie und Onkologie. 171(1). 29-34 (1995)
Shimizutani,K.,Inoue To.:“^<198>Au 颗粒在口腔癌中的应用。”
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Inoue,Ta.,Inoue,To.: "Phase III trial of high and low dose rate interstitial radiotherapy for early oral tongue cancer." Intermational Journal of Radiation Oncology Biology Physics. 36. 1201-1204 (1996)
Inoue, Ta., Inoue, To.:“早期口腔舌癌高剂量率和低剂量率间质放射治疗的 III 期试验。”
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Fournier-Bidoz,N.,Inoue,To.: "On the clinical use of the Anderson dose-volume histogram to evaluate interstitial implants." Endocurietherapy Hyperthermia Oncology. (in press). (1997)
Fournier-Bidoz,N.,Inoue,To.:“关于安德森剂量体积直方图评估间质植入物的临床应用。”
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Exhaled nitric oxide and radiation pneumonitis
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批准号:10470195
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$2.56万
-
财政年份:1998
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负责人:INOUE Toshihiko
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依托单位:
High dose rate fractionated interstitial radiation as an alternative to low dose rate continuous interstitial radiation
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批准号:06304032
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项目类别:Grant-in-Aid for Co-operative Research (A)
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资助金额:$7.81万
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财政年份:1994
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负责人:INOUE Toshihiko
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依托单位:
海外基金