Basic study on developments of foods having a function that, enhances endurance capacity

具有增强耐力功能的食品开发的基础研究

• 批准号: 07456061
• 负责人: FUSHIKI Tohru
• 金额: $ 0.77万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1996
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07456061/
• 关键词: endurance capacity; swimming system; mice; foods; evaluation of the endurance capacity; 運動能力増強; 体力; 運動能力

A new forced swimming apparatus for determining maximum swimming time in mice was devised for use in evaluations of the endurance capacity. of mice following various treatments with diet and drugs. A water current generated by circulating water with a pump was developed in a swimming pool. A spout and suction slit were contrived to generate a constant current while the strength of the current was regulated by a valve. The decrease of the leg kicking intervals of mice accompanying increase in the current speed was confirmation that the work load is adjustable by regulation of current speed. The hind legs were most used by mice in this apparatus when compared the kicking intervals to forelegs paddling intervals. That swimming time until fatigue was decreased with relationship to increasing current speed was confirmed in two strains of mice. As biochemical indexes, blood lactate and muscle glycogen levels corroborated the correlation between current speed and increase in work load. These results indicate that the apparatus employed in the present study offers many advantages in the evaluation of the endurance capacity of mice, and is useful for detecting the effects of diets and drugs on this capacity.

设计了一种新的测定小鼠最大游泳时间的强迫游泳装置，用于评价小鼠的耐力。对小鼠进行饮食和药物治疗。在游泳池中开发了一种通过泵循环水产生的水流。设计了一个喷口和一个抽吸狭缝来产生恒定的电流，而电流的强度由一个阀门来调节。随着电流速度的增加，小鼠的腿踢间隔减小，这证实了通过调节电流速度可以调节工作负荷。在该装置中，当比较踢腿间隔与前腿划水间隔时，小鼠最常使用后腿。在两个品系的小鼠中证实了直到疲劳的游泳时间随着电流速度的增加而减少。血乳酸和肌糖原水平作为生化指标，证实了当前速度与工作负荷增加之间的相关性。这些结果表明，在本研究中使用的装置提供了许多优点，在评价小鼠的耐力，并用于检测饮食和药物对这种能力的影响。

项目成果

K.Matsumoto, K.Ishiohara, K.Tanaka, K.Inoue, T.Fushiki: "An adjustable-current swimming pool for the evaluation of endurance capacity of mice" J.Appl.Physiol. 81(4). 1843-1849 (1996)

K.Matsumoto、K.Ishiohara、K.Tanaka、K.Inoue、T.Fushiki：“用于评估小鼠耐力能力的可调电流游泳池”J.Appl.Physiol。

KEITARO MATSUMOTO: "An adjustable-current swimming pool for the evaluation of endurance capacity of mice" J. Appl. Physiol.81 (4). 1843-1849 (1996)

松本庆太郎：“用于评估小鼠耐力能力的可调电流游泳池”J. Appl。

KEITARO MATSUMOTO: "An adjustable-current swimming pool for the evaluation of endurance capacity of mice" J.Appl.Physiol.81(4). 1843-1849 (1996)

KEITARO MATSUMOTO：“用于评估小鼠耐力能力的可调电流游泳池”J.Appl.Physiol.81(4)。

T. Fushiki et. al.: "Swimming endurance capacity of mice is increased by chronic consumptign of medium-chain trigtycerides" J. Nutrition. 125. 531-539 (1995)

T. Fushiki 等。