Non-destructive detection of material fatigue in artificial heart by ultrasonic spectroscopy.
超声光谱无损检测人工心脏材料疲劳
基本信息
- 批准号:07458234
- 负责人:
- 金额:$ 4.1万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (B)
- 财政年份:1995
- 资助国家:日本
- 起止时间:1995 至 1996
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Left ventricular assist device (LVAD) has been clinically applied for the treatment of severe heart failure in recent years. As the period of using LVAD is expanded to nearly one year, the detection of material damage has been necessitated. In order to detect the material fatigue, low frequency ultrasonic properties of the material were assessed by the frequency domain analysis of the pulsed ultrasound, and the surface morphology of the material was visualized by the acoustic microscopy.A3.5 MHz linear transducer was placed above the sample in a water tank. The system was modified to access to the rf signals at the output of the time gain controlled (TCG) amplifier, before any significant nonlinear processing, such as compression or rectification, was performed. To observe the frequency dependent characteristics of the received pulse, the Fast Fourier Transform (FFT) of the data was computed. The significant differences of FFT waveforms were observed between new and fatigued materials. Ultrasonic method could detect the material fatigue, although the appearance and the thickness of the samples did not show significant change.A specially developed scanning acoustic microscope system, operating in the frequency range of 100-200MHz, was employed. In the amplitude image of new material, there were no significant cracks or abnormal structure on the surface. Although the surface seemed to be smooth in the amplitude image, the surface was found to be distorted in the phase image. Very small crack and abnormal powder structure was detected in the amplitude image. In the phase image, the distortion was more prominent than that of new material.Both in low and high frequencies, ultrasonic approaches to evaluate the material revealed the material damage. Although this study was performed in the static condition, ultrasonic method should be used in the beating condition in the next stage investigation.
左心室辅助装置(LVAD)是近年来临床上应用于治疗严重心力衰竭的一种新型装置。随着LVAD的使用时间延长到近一年,有必要检测材料损坏。为了检测材料的疲劳性能,采用低频脉冲超声频域分析法对材料的超声特性进行了评价,并采用声显微镜观察了材料的表面形貌。该系统被修改为在执行任何重要的非线性处理(例如压缩或整流)之前访问时间增益控制(TCG)放大器的输出处的RF信号。为了观察接收脉冲的频率依赖特性,计算数据的快速傅立叶变换(FFT)。新材料和疲劳材料的FFT波形存在显著差异。超声方法可以检测材料的疲劳,虽然样品的外观和厚度没有显着变化,一个专门开发的扫描声显微镜系统,工作频率范围为100- 200 MHz。在新材料的振幅图像中,表面没有明显的裂纹或异常结构。虽然表面在振幅图像中似乎是平滑的,但在相位图像中发现表面是扭曲的。在振幅图像中检测到非常小的裂纹和异常粉末结构。在相位图中,变形比新材料的变形更明显,无论在低频还是高频,超声方法都能揭示材料的损伤。虽然本研究是在静态条件下进行的,但在下一阶段的研究中,应使用超声方法在打浆条件下进行。
项目成果
期刊论文数量(22)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
S.Nitta et al.: "Totally implantable ventricular assist system using a vibrating flow pump" Artif Organs. 19. 676-679 (1995)
S.Nitta 等人:“使用振动流泵的完全植入式心室辅助系统”Artif Organs。
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- 影响因子:0
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- 通讯作者:
Y.Saijo, S.Nitta et.al: "Ultrasonic properties of myocardium in low MHz frequencies assessed by acoustic microscopy" Eur J Ultrasound in Med & Biol. vol 4. s64 (1996)
Y.Saijo、S.Nitta 等人:“通过声学显微镜评估低 MHz 频率心肌的超声特性”Eur J Ultrasound in Med
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- 影响因子:0
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Y. Saijo, S. Nitta et al.: "Development of ultrasonic spectroscopy for biomedical use" Acoustical Imaging. 22. 335-340 (1995)
Y. Saijo、S. Nitta 等人:“生物医学用途超声波光谱的发展”声学成像。
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- 影响因子:0
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Y.Saijo,S.Nitta et al.: "Frequency dependent characteristics of ultrasonic attenuation in liver tissue" Proc 1st World Congress on Ultrasonics. 1059-1062 (1995)
Y.Saijo、S.Nitta 等人:“肝脏组织中超声衰减的频率相关特征”Proc 第一届世界超声大会。
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- 影响因子:0
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S.Kobayashi, S.Nitta el.al: "Experimental study of physiological advantages of assist circulation using oscillated blood flow." Artificial Organs. vol 19. 704-707 (1995)
S.Kobayashi、S.Nitta el.al:“利用振荡血流辅助循环的生理优势的实验研究。”
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NITTA Shin-ichi其他文献
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{{ truncateString('NITTA Shin-ichi', 18)}}的其他基金
Development of a physiologically effective control system for an artificial heart based on autonomic nerve activity
基于自主神经活动的人工心脏生理有效控制系统的开发
- 批准号:
12308045 - 财政年份:2000
- 资助金额:
$ 4.1万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
DRUG DELIVERY SYSTEM BY THE CONTROL OF BLOOD FLOW DISTRIBUTION USING ARTIFICIAL CIRCULATION WITH OSCILLATED BLOOD FLOW
通过使用具有振荡血流的人工循环来控制血流分布的药物输送系统
- 批准号:
07557309 - 财政年份:1995
- 资助金额:
$ 4.1万 - 项目类别:
Grant-in-Aid for Scientific Research (A)
BASIC RESEARCH ABOUT THE CLINICAL APPLICATION OF THE ARTIFICIAL HEART FOR THE BRIDGING USE OF THE HEART TRANSPLANTATION
人工心脏作为心脏移植桥接用途的临床应用基础研究
- 批准号:
63570656 - 财政年份:1988
- 资助金额:
$ 4.1万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
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