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Development of depth dose meter for heavy ion particle beams with piled plastic scintillators

Development of depth dose meter for heavy ion particle beams with piled plastic scintillators
堆积塑料闪烁体重离子粒子束深度剂量计的研制
批准号:
07507005
负责人:
INOUE Toshihiro
金额:
$1.28万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1996

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项目成果

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中文摘要
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英文摘要
We continued to test the new developed depth dose meter. The dosimeter was exposed to x rays (4,10 and 18 MV) and electron beams (6,9,12 and 15 MeV) from Linac at the Osaka University Hospital, proton beams (65 and 200 MeV) from the cyclotron at RCNP of Osaka University and carbon beam (290MeV/n) from the Heavy Ion of Medical Accerator in Chiba of NIRS to test it. The pressed type of fiberblock without heat is more suitable for sensor than that with heat in respect of shielding the light. We could decrease the background signal in obtaining the image data by utilizing the digital filter. The fitness was good between the depth dose data by ionization chamber and by new dosimeter after compensating Cerenkov light for X ray and electron beam, quenching of light by energetic proton beams. The discrepancy became smaller by compensating the characteristics of emission of light from fiberblock. We could measure the depth dose curve for mono peak beam of carbon. But the discrepancy was large for spread outed carbon beams containing different components of LET.There are much room for improvement. After confirming the high quality of depth dose meter by correcting the difference of light emission by variable particles, we have a plan to make more compact 3D depth dose meter with rotation and rectilinear motion of detector. Such a new designed dosimeter will be useful because of reducing time for measurement of the fundamental dose distribution.
期刊论文(10)
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会议论文
福島祥子: "陽子線と炭素線照射によるヒトリンパ芽球系細胞でのアポトーシス誘導" 日放腫会誌. 8(suppl 1). 280- (1996)
Sachiko Fukushima:“通过质子束和碳离子照射诱导人淋巴母细胞凋亡”,日本放射治疗学会杂志 8(增刊 1)。
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井上俊彦: "重粒子線照射によるcell cycle arrestに対するp53の関与" 平成7年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書. 105-106 (1996)
Toshihiko Inoue:“p53参与重离子束照射引起的细胞周期停滞”1995年国立放射线科学研究所联合使用重离子癌症治疗设备研究报告105-106(1996)。
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Fukushima, S.: "Cell cycle kinetics and p53 protein induction in human lymphoblast cell lines following exposure to 65 MeV proton beam." RCNP Annual Report 1995. 66-69 (1996)
Fukushima, S.:“暴露于 65 MeV 质子束后人淋巴母细胞系的细胞周期动力学和 p53 蛋白诱导。”
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10
    Comprehensive investigation of tension-sensitive factors that related to changes in cytoskeleton and cell adhesion in trabecular meshwork cells
    • 批准号:
      23791994
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.66万
    • 财政年份:
      2011
    • 负责人:
      INOUE Toshihiro
    • 依托单位:
    Research for associations of tension-dependent aqueous outflow regulation by trabecular meshwork with glaucoma pathology.
    • 批准号:
      21791693
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.25万
    • 财政年份:
      2009
    • 负责人:
      INOUE Toshihiro
    • 依托单位: