Glycan-based prebiotic approaches to increase food safety in Australia

基于聚糖的益生元方法可提高澳大利亚的食品安全

• 批准号: DP220102820
• 负责人: A/Prof Thomas Haselhorst
• 金额: $ 37.75万
• 依托单位: Griffith University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220102820
• 关键词: Glycan; based; prebiotic; approaches; increase

Since the launch of the first Australian Animal Sector National Antimicrobial Resistance Plan (2018) several approaches have been suggested to reduce the use antibiotics in agriculture, however no alternatives to antibiotics have been suggested or trialled. In this proposal we aim to develop a novel glycan-based prebiotic strategy to reduce Campylobacter jejuni colonisation in chicken and poultry by disrupting important glycan-glycan interactions. Outcomes of this proposal is a cost-effective antibiotic- and vaccine-independent animal feed supplement strategy that will decrease the risk of human food-borne illness and therefore promoting food safety and public health in Australia.

自2018年第一个澳大利亚动物部门国家抗菌素耐药性计划（Australian Animal Sector National Antimicrobial Resistance Plan）推出以来，已经提出了几种方法来减少农业中抗生素的使用，但尚未提出或试验抗生素的替代品。在这项提案中，我们的目标是开发一种新的基于聚糖的益生元策略，通过破坏重要的聚糖-聚糖相互作用来减少空肠弯曲菌在鸡和家禽中的定殖。该提案的结果是一个具有成本效益的抗生素和疫苗独立的动物饲料补充战略，将降低人类食源性疾病的风险，从而促进澳大利亚的食品安全和公共卫生。