Mobile System for Functional Near-Infrared Spectroscopy (fNIRS)

功能性近红外光谱移动系统 (fNIRS)

• 批准号: 527194510
• 金额: --
• 依托单位: Eberhard Karls Universität Tübingen
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/527194510?language=en
• 关键词: Mobile; System; Functional; Near; Infrared

The research focus of the applying department is the investigation of the fundamental mechanisms involved in the development and maintenance of pathological eating behavior and body image disorder. Imaging methods provide insights into the neural correlates of such mechanisms and thus contribute significantly to a fundamental understanding. In order to realize the research ambitions of the department, neuroimaging and training studies in outpatient settings will continue to be carried out in particular. In recent years, this core competence has been strengthened in the growing working group. For the department's research projects, a mobile system for functional near-infrared spectroscopy (fNIRS) is needed, which can flexibly and in different scenarios investigate cortical activations. Due to rapid hardware developments in fNIRS research, mobile devices are now available that allow for studies on patients in outpatient settings and in economically valid scenarios, e.g. during exposure or eating-related tasks. In particular, the correction for extracerebral signals, which are only made possible by newer devices with short-distance channels, is noteworthy. This keeps research competitive in the long-term and results are not confounded by motor artifacts. The requested device is compatible with other relevant methods of the research group, particularly tDCS, EEG, eye-tracking, and VR. A minimum number of 32 high-quality optode pairs (32 sources, 32 detectors) is required to cover the cortical areas that are relevant to current and future research projects. A compatible multichannel stimulator is additionally requested that will be used in combination with fNIRS, but which is distinct from other neurostimulation projects. The overall system must be suitable and approved for research on adult and pediatric patients. In Tübingen, there is already a lot of experience with fNIRS in various departments, and a network for methodological and content exchange. In 2021, researchers of the department, together with colleagues from cognitive neuropsychology, the clinic for psychiatry and psychotherapy, as well as the institute for diabetes research and metabolic diseases, organized an international, intramural-funded fNIRS summer school. Close networking between the departments and joint research projects strengthen the methodological expertise and social contribution of the location and its networking with international partners. Therefore, the acquisition of this mobile fNIRS system will significantly contribute to the department's research capabilities and allow for more flexible and efficient research and collaboration.

应用部门的研究重点是探讨病理性进食行为和身体形象障碍发生和维持的基本机制。成像方法提供了对这种机制的神经关联的洞察，因此对基本的理解有很大的贡献。为了实现科室的研究抱负，将继续特别在门诊环境中进行神经成像和培训研究。近年来，这一核心能力在不断壮大的工作组中得到了加强。对于该部门的研究项目，需要一种功能近红外光谱(FNIRS)的移动系统，该系统可以灵活地在不同的情况下调查大脑皮质的激活。由于fNIRS研究中硬件的快速发展，现在可以使用移动设备在门诊环境中和在经济有效的情况下对患者进行研究，例如在暴露或与饮食相关的任务期间。尤其值得注意的是，对脑外信号的校正只有通过具有短距离频道的新型设备才能实现。从长远来看，这将使研究保持竞争力，结果不会受到汽车假象的干扰。所要求的设备与课题组的其他相关方法兼容，特别是tDCS、EEG、眼球跟踪和VR。至少需要32对高质量的光电管(32个光源，32个探测器)，以覆盖与当前和未来研究项目相关的皮质区域。另外还需要一个兼容的多通道刺激器，该刺激器将与fNIRS结合使用，但与其他神经刺激项目不同。整个系统必须适用于成人和儿科患者的研究，并获得批准。在Tübingen，各个部门已经有了很多使用fNIRS的经验，并建立了一个方法和内容交流网络。2021年，该系的研究人员与认知神经心理学、精神病学和心理治疗诊所以及糖尿病研究和代谢性疾病研究所的同事一起，组织了一次由校内资助的国际fnirs暑期学校。这两个部之间的密切联系和联合研究项目加强了该地点的方法专门知识和社会贡献，并加强了该地点与国际伙伴的联系。因此，收购这一移动fNIRS系统将极大地促进该部门的研究能力，并允许更灵活和有效的研究与合作。