A Neurophysiological Study of Roles of Motor Areas in Primate Cortex for Mastication

灵长类动物皮层咀嚼运动区作用的神经生理学研究

• 批准号: 07838033
• 负责人: YOSHINO Kenichi
• 金额: $ 1.66万
• 依托单位: KYUSHU DENTAL COLLEGE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07838033/
• 关键词: VISUALLY GUIDED JAW MOVEMENT TASK; PRIMATE; PREMOTOR CORTEX; PRIMARY MOTOR CORTEX; SINGLE NEURONAL ACTIVITY

Neuronal activities in the ventral part of the premotor cortex (PMv) and the primary motor cortex (MI) were analyzed during a visually guided jaw movement task. Based on the type of neuronal activity observed, when monkeys closed or opened their mouths in response to a visual stimulus, PMv neurons could be classified into three categories : 1)signal-related neurons, which transiently responded to visual stimuli, 2)movement-related neurons, which were time-locked to Jaw opening and/or jaw closing movements, and 3)set-related neurons which exhibited gradually increasing activities while jaw position was maintained. However, all MI neurons exhibited movement-related activities and responded differently between the closing and opening dynamic phases. These results suggest that PMv neurons may be involved in motor preparation, initiation and control of jaw movements and task behavior based on visual information, and that MI neurons may be involved in controlling jaw movements, especially contraction of the masticatory muscles.

在视觉引导的下颌运动任务中，分析了运动前区皮层（PMv）和初级运动皮层（MI）腹侧部分的神经元活动。根据观察到的神经元活动类型，当猴子闭上或张开嘴以响应视觉刺激时，PMv神经元可以分为三类：1）信号相关神经元，其对视觉刺激作出短暂反应，2）运动相关神经元，其对下颌张开和/或下颌闭合运动进行时间锁定，（3）在保持颌位的同时，集合相关神经元的活动逐渐增强。然而，所有MI神经元表现出运动相关的活动，并作出不同的反应之间的关闭和开放的动态阶段。这些结果表明，PMv神经元可能参与运动准备，启动和控制下颌运动和任务行为的基础上的视觉信息，和MI神经元可能参与控制下颌运动，特别是咀嚼肌的收缩。

项目成果

吉野 賢一: "視覚に誘導される顎運動課題遂行時の運動前野の役割" 口腔保健協会, 4 (1997)

Kenichi Yoshino：“前运动皮层在视觉引导下颌运动任务中的作用”口腔健康协会，4 (1997)

吉野 賢一: "脳の謎を解く「かむと頭がよくなるってホント」" 朝日新聞社, 11 (1995)

吉野健一：“解开大脑之谜：‘咀嚼确实能让人变得更聪明’”《朝日新闻》，11 (1995)

吉野 賢一: "視覚誘導性顎運動課題における運動前野の役割" 霊長類研究所年報. 26. 98-98 (1996)

Kenichi Yoshino：“前运动皮层在视觉引导下颌运动任务中的作用”灵长类研究所年度报告 26. 98-98 (1996)。

Yoshino, K., Mikami, A.and Kubota, K.: "neuronal Activities in the Ventral Premotor Cortex During a Visually Guided Jaw Movement in Monkey" Neuroscience Research. (1998)

Yoshino, K.、Mikami, A. 和 Kubota, K.：“猴子视觉引导下颌运动期间腹侧前运动皮层的神经元活动”神经科学研究。

吉野賢一: "視覚誘導性顎運動課題における運動前野の役割" 霊長類研究所年報. 26. 98-98 (1996)

Kenichi Yoshino：“前运动皮层在视觉引导下颌运动任务中的作用”灵长类研究所年度报告 26. 98-98 (1996)。