State-of-the-art housing to expand the Emory National Primate Research Center SPF rhesus macaque breeding colony

最先进的住房用于扩大埃默里国家灵长类研究中心 SPF 恒河猴繁殖群

• 批准号: 10795471
• 负责人: Joyce Kimberly Cohen
• 金额: $ 799.61万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10795471
• 关键词: Address; Animal Housing; Animal Welfare; Animals; Breeding; Genetic; Housing; Human Resources; Macaca mulatta; Primates; Program Research Project Grants; Research; Research Personnel; Running; design; improved; nonhuman primate; novel; social group

Abstract The robust nonhuman primate research portfolio at the Emory National Primate Research Center (ENPRC), which reached $36.8M in FY2022, has placed significant and unsustainable demands on the Emory NPRC rhesus macaque SPF breeding colony. To meet the current and projected future research demand, ENPRC is proposing to build new animal housing at the ENPRC Field Station to facilitate expansion of the SPF breeding colony. The new animal housing proposed will be a novel housing design that integrates traditional large indoor/ outdoor breeding spaces into a building that includes smaller run housing space as well as animal support space. The run housing will be comprised of traditional indoor run space with accompanying enlarged outdoor run space to facilitate larger social groupings. This combination of compound and run space will maximize breeding potential and facilitate targeted genetic breeding in run groups to support specific research requests and enable colony management needs. The new building will enhance animal welfare with natural substrate in the runs as well as the outdoor compound and include functional features incorporated into the design that will improve animal handling and increase efficiency for personnel. The proposed new animal housing at the Field Station will allow for significant expansion of the SPF rhesus macaque colony over the next five years, thus providing additional animals to support the current research and projected research program for investigators at Emory NPRC as well as for external collaborators to address the nationwide shortage of NHPs for research.

抽象的 Emory国家灵长类动物研究的强大非人类灵长类动物研究组合 Center（ENPRC）在2022财年达到3680万美元，已经放置了重大且不可持续的 对Emory NPRC猕猴SPF繁殖菌落的需求。满足电流和 预计未来的研究需求，ENP​​RC建议在 ENPRC现场站促进SPF繁殖菌落的扩展。新动物 提议的住房将是一种新颖的住房设计，该设计整合了传统的大型室内/室外 繁殖空间进入建筑物，其中包括较小的住房空间以及动物 支持空间。跑步住房将由传统的室内跑步空间组成 伴随着扩大的室外跑步空间，以促进更大的社会团体。这 化合物和跑步空间的组合将最大化育种潜力并促进目标 运行组中的基因育种，以支持特定的研究请求并实现殖民地 管理需求。新建筑将通过自然基材增强动物福利 运行以及室外化合物，并包含包含的功能功能 设计将改善动物处理并提高人员效率。提议 现场站的新动物外壳将允许大幅扩大SPF恒河猴 在接下来的五年中，猕猴的殖民地，从而提供了更多的动物来支持 当前针对Emory NPRC研究人员的研究和预计研究计划 让外部合作者解决全国NHP的研究短缺。