State-of-the-art housing to expand the Emory National Primate Research Center SPF rhesus macaque breeding colony

最先进的住房用于扩大埃默里国家灵长类研究中心 SPF 恒河猴繁殖群

• 批准号: 10795471
• 负责人: Joyce Kimberly Cohen
• 金额: $ 799.61万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10795471
• 关键词: Address; Animal Housing; Animal Welfare; Animals; Breeding; Genetic; Housing; Human Resources; Macaca mulatta; Primates; Program Research Project Grants; Research; Research Personnel; Running; design; improved; nonhuman primate; novel; social group

Abstract The robust nonhuman primate research portfolio at the Emory National Primate Research Center (ENPRC), which reached $36.8M in FY2022, has placed significant and unsustainable demands on the Emory NPRC rhesus macaque SPF breeding colony. To meet the current and projected future research demand, ENPRC is proposing to build new animal housing at the ENPRC Field Station to facilitate expansion of the SPF breeding colony. The new animal housing proposed will be a novel housing design that integrates traditional large indoor/ outdoor breeding spaces into a building that includes smaller run housing space as well as animal support space. The run housing will be comprised of traditional indoor run space with accompanying enlarged outdoor run space to facilitate larger social groupings. This combination of compound and run space will maximize breeding potential and facilitate targeted genetic breeding in run groups to support specific research requests and enable colony management needs. The new building will enhance animal welfare with natural substrate in the runs as well as the outdoor compound and include functional features incorporated into the design that will improve animal handling and increase efficiency for personnel. The proposed new animal housing at the Field Station will allow for significant expansion of the SPF rhesus macaque colony over the next five years, thus providing additional animals to support the current research and projected research program for investigators at Emory NPRC as well as for external collaborators to address the nationwide shortage of NHPs for research.

抽象的 埃默里国家灵长类研究中心强大的非人类灵长类研究组合 Center (ENPRC) 在 2022 财年达到 3680 万美元，已投入大量且不可持续的资金 对埃默里 NPRC 恒河猴 SPF 繁殖群的要求。为满足当前和 预计未来的研究需求，ENP​​RC 提议在 ENPRC 野外站促进 SPF 繁殖群体的扩张。新动物 拟议的住房将是一种新颖的住房设计，融合了传统的大型室内/室外 将繁殖空间融入建筑物中，其中包括较小的运行住房空间以及动物 支持空间。运行房屋将由传统的室内运行空间组成 伴随着扩大的户外跑步空间，以促进更大的社交团体。这 复合物和运行空间的结合将最大限度地发挥育种潜力并促进有针对性的 在运行小组中进行遗传育种，以支持特定的研究要求并启用群体 管理需求。新建筑将利用自然基质提高动物福利 与室外庭院一样运行，并包括融入到的功能特征 设计将改善动物处理并提高人员效率。拟议的 野外站的新动物圈舍将使 SPF 恒河猴的数量大幅增加 未来五年的猕猴群落，从而提供更多的动物来支持 埃默里 NPRC 的研究人员当前的研究和预计的研究计划以及 为外部合作者提供帮助，以解决全国范围内用于研究的 NHP 短缺问题。