State-of-the-art housing to expand the Emory National Primate Research Center SPF rhesus macaque breeding colony

最先进的住房用于扩大埃默里国家灵长类研究中心 SPF 恒河猴繁殖群

• 批准号: 10795471
• 负责人: Joyce Kimberly Cohen
• 金额: $ 799.61万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10795471
• 关键词: Address; Animal Housing; Animal Welfare; Animals; Breeding; Genetic; Housing; Human Resources; Macaca mulatta; Primates; Program Research Project Grants; Research; Research Personnel; Running; design; improved; nonhuman primate; novel; social group

Abstract The robust nonhuman primate research portfolio at the Emory National Primate Research Center (ENPRC), which reached $36.8M in FY2022, has placed significant and unsustainable demands on the Emory NPRC rhesus macaque SPF breeding colony. To meet the current and projected future research demand, ENPRC is proposing to build new animal housing at the ENPRC Field Station to facilitate expansion of the SPF breeding colony. The new animal housing proposed will be a novel housing design that integrates traditional large indoor/ outdoor breeding spaces into a building that includes smaller run housing space as well as animal support space. The run housing will be comprised of traditional indoor run space with accompanying enlarged outdoor run space to facilitate larger social groupings. This combination of compound and run space will maximize breeding potential and facilitate targeted genetic breeding in run groups to support specific research requests and enable colony management needs. The new building will enhance animal welfare with natural substrate in the runs as well as the outdoor compound and include functional features incorporated into the design that will improve animal handling and increase efficiency for personnel. The proposed new animal housing at the Field Station will allow for significant expansion of the SPF rhesus macaque colony over the next five years, thus providing additional animals to support the current research and projected research program for investigators at Emory NPRC as well as for external collaborators to address the nationwide shortage of NHPs for research.

摘要 埃默里国家灵长类动物研究中心（Emory National Primate Research） 中心（ENPRC），在2022财年达到3680万美元， 对Emory NPRC恒河猴SPF繁殖群的要求。为了满足当前和 预计未来的研究需求，ENPRC建议在 ENPRC野外工作站，以促进SPF繁殖群的扩大。新动物 一种新型的住宅设计，将传统的大型室内/室外 饲养空间到一个建筑物，包括较小的运行住房空间，以及动物 支持空间。跑步房将由传统的室内跑步空间组成， 伴随着扩大的户外跑步空间，以促进更大的社会群体。这 混合物和运行空间的组合将最大限度地提高育种潜力， 在运行组中进行遗传育种，以支持特定的研究要求， 管理需要。新建筑将以天然基质改善动物福利， 运行以及室外化合物，并包括功能特点纳入 设计将改善动物处理和提高工作人员的效率。拟议 野外站的新动物舍将允许SPF恒河猴的显著扩张 猕猴殖民地在未来五年，从而提供额外的动物，以支持 目前的研究和计划的研究计划，为调查人员在埃默里npr以及 为外部合作者解决全国范围内缺乏NHP的研究。