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Search for the salivary proline-rich peptide P-B related genes

Search for the salivary proline-rich peptide P-B related genes
寻找唾液富含脯氨酸肽P-B相关基因
批准号:
07672034
负责人:
ISEMURA Satoko
金额:
$0.96万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1995
资助国家:
日本
项目状态:
已结题
起止时间:
1995 至 1997

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中文摘要
翻译
PBI基因是唾液富含脯氨酸蛋白P-B的一个推定翻译产物,其核苷酸序列已被确定。PBI全长6.4kb,包含3个外显子。目前的结果表明,PBI能够编码富含脯氨酸的蛋白前体,我们将其命名为P-B1。P-B1前体由134个氨基酸残基组成,包括信号序列22个残基、n端序列23个残基、13 ~ 14个残基的5个重复单元和c端序列22个残基。该前体的信号序列与P-b前体的信号序列相同。P-B1 n端61个残基序列与P-B全序列(57个残基)相比,考虑4个残基的缺失,同源性为75%。P-B1比b长55个残基。
英文摘要
The nucleotide sequence of gene PBI,a putativetranslational product of which is homologous to salivary prolin-rich protein P-B has been determined. PBI is 6.4kb long and contains 3 exons. The present result indicates that PBI is capable of coding for the precursor of proline-rich protein which we have designated P-B1. The P-B1 precursor is composed of 134 amino acid residues including 22 residues of signal sequence, 23 residues of N-terminal sequence, five repeating units of 13 to 14 residues and 22 residues of C-terminal sequence. The signal sequence of this precursor is identical with that of the P-b precursor. The N-terminal 61 residue sequence of P-B1 has homology of 75% as compared with the whole sequence of P-B (57 residues), when deletion of 4 residues is taken into account. P-B1 is 55 residues longer than P-B.
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Role of salivary proline-rich protein P-B in cell differenciation.
Molecular genetical and phylogenic studies on human salivary proline-rich protein P-B.
Molecular cloning of cDNA coding for the salivary proline-rich peptide P-B
Studies on the cysteine proteinase inhibitor (cystatin S)
  • 批准号:
    60580141
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)
  • 资助金额:
    $1.02万
  • 财政年份:
    1985
  • 负责人:
    ISEMURA Satoko
  • 依托单位:
海外基金