LOGITUDINAL STUDY ON INFULENCE OF CHILD REARING ENVIRONMENT TO DEVELOPMENT OF SLEEP AND BEHAVIOR IN PREMATURE INFANTS.

儿童养育环境对早产儿睡眠及行为发展影响的追踪研究。

• 批准号: 07672522
• 负责人: HORIUCHI Kentaroh
• 金额: $ 1.66万
• 依托单位: HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07672522/
• 关键词: SLEEP-WAKE RHYTHM; CIRCADIAN RHYTHM; CORTISOL; DEVELOPMENT; BEHEVIOR; INFANTS; SALIVA; ELISA; ルチゾール

The purpose of this study were to investigate (1) longitudinal influence of constant light in neonatal care unit to biological rhythm and behavior in childhood of preterm infants, and (2) devlopmental retardation of sleep-wake rhythm in preterm infants who admitted in neonatal care unit with constant light in the long term onward 44 corrected weeks. As results, 44 preterm infants caught up in a given postnatal period, to show no differences in sleep-wake rhythm, circadian rhythm of saliva cortisol, and behavior development in childhood, from 40 term infants in the same postnatal 2 to 4 year of age.We first found also that the 8 preterm infants in neonatal intensive care unit had significant smaller wakefulness time than 44 preterm infanrts who had discharged from there around 40 corrected weeks, and that they slept longer in day time than in night. They indicated difficulty in entrainment of diurnal rhythm in neonatal care unit.

本研究的目的是调查（1）新生儿护理病房中的恒定光对早产儿儿童期生物节律和行为的纵向影响，以及（2）在 44 校正周后的长期内，入住恒定光新生儿护理病房的早产儿的睡眠-觉醒节律发育迟缓。结果，44 名早产儿在特定的产后阶段，与同一产后 2 至 4 岁的 40 名足月儿相比，在睡眠-觉醒节律、唾液皮质醇的昼夜节律和儿童期行为发育方面没有差异。我们还首先发现，新生儿重症监护病房中的 8 名早产儿的觉醒时间明显小于已出院的 44 名早产儿。 从那时起，经过大约 40 周的修正，他们白天的睡眠时间比晚上的时间更长。他们指出新生儿护理病房很难控制昼夜节律。

项目成果

島田 三恵子、他: "1日リズムを確立できない乳児に対する育児援助。" 母性衛生. 39(印刷中). (1998)

Mieko Shimada 等人：“为无法建立日常节奏的婴儿提供育儿支持。”39（出版中）。

Satoshi TAMOTSU, Michikazu SAMEJIMA: "Three-Dimensional Reconstruction of Serotonine-Immunoreactive Photoreceptors in the Pineal Organ of the River Lamprey, Lampetra japonica." Biological Signals. 6. 184-190 (1997)

Satoshi TAMOTSU、Michikazu SAMEJIMA：“日本七鳃鳗松果体中血清素免疫反应光感受器的三维重建。”

Satoshi Tamotsu,Michikazu Samejima, et al.: "Three-Dimensional Reconstruction of Serotonine-Immunoreactive photoreceptors in the Pineal organ of the River Lamprey,Lampetra japonica." Biological Signals. 6. 184-190 (199)

Satoshi Tamotsu、Michikazu Samejima 等人：“日本七鳃鳗松果体器官中血清素免疫反应光感受器的三维重建”。

鮫島道和、保智巳: "パーソナルコンピュータを用いたアナログデータ処理。" 日本生理学会誌. 59(10). 431-438 (1997)

Michikazu Samejima，Tomomi Yasushi：“使用个人计算机进行模拟数据处理。”日本生理学会杂志 59(10) (1997)。

Mieko SHIMADA,et al.: "Determination of Salivary Cortisol by ELISA and its application to the Assessment of the Circadian Rhyhm in Chilren." Hormone Research. vol.44. 213-217 (1995)

Mieko Shimada 等人：“通过 ELISA 测定唾液皮质醇及其在儿童昼夜节律评估中的应用”。