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Clinical Study on Bruxism in Human during Sleep

人类睡眠期间磨牙症的临床研究

基本信息

批准号：
08407065
负责人：
KOBAYASHI Yoshinori
金额：
$ 21.89万
依托单位：
The Nippon Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1999
项目状态：
已结题

项目摘要

In most of the recent researches on bruxism wired recording devices were used, but the constrained feeling from the wires affected the central nerves system (CNS) and an accurate recording of biological phenomena could not be made. Also the portable wireless EMG type device gave rather inaccurate recordings and could not record the sleep condition and other biological conditions which were intimately related to bruxism.Therefore in this experiment using a small wireless telemeter a system that will record and analyze the biological phenomena during sleep at night was developed. And in order to clarify sleep condition of human especially that of bruxism the biological phenomena of normal subjects, bruxists, CMD patients, and edentulous patients during sleep at night were analyzed. The results were as follows.A system that can monitor biological phenomena of human during sleep at night, and that can evaluate quantitatively and visually the relation between brain wave sleep stages and bruxism during sleep at night was developed. Total sleep time were about the same for normal subjects, bruxists, CMD patients and edentulous patients. It was clear that compared to normal subject group, both bruxist group and CMD patients group had significantly high frequency of bruxism, significantly high frequency of transition between sleep stages, significantly high frequency of stage 1 and significantly low incidence of stage REM, and was suffering from sleep disorder. It was also clear that bruxism during sleep at night for edentulous patients were at a level lower than that of normal subjects with teeth if it was functionally stable and that they were less likely to have masticatory dysfnction initiated by bruxism during sleep at night.

近年来对磨牙症的研究大多采用有线记录装置，但由于有线的束缚感影响了中枢神经系统，无法准确记录生物现象。此外，便携式无线肌电图设备的记录相当不准确，不能记录与磨牙症密切相关的睡眠状况和其他生物状况。因此，本实验利用小型无线遥测仪研制了一套记录和分析夜间睡眠生物现象的系统。为了弄清人类特别是磨牙患者的睡眠状况，对正常人、磨牙患者、CMD患者和无牙患者夜间睡眠的生物学现象进行了分析。结果如下：研制了一种夜间睡眠生物现象监测系统，可定量、直观地评价夜间睡眠时脑电波睡眠阶段与磨牙症之间的关系。正常受试者、磨牙患者、CMD患者和无牙患者的总睡眠时间大致相同。可见，与正常受试者组相比，磨牙组和CMD患者组的磨牙频率显著高，睡眠阶段转换频率显著高，第一阶段频率显著高，快速眼动阶段发生率显著低，存在睡眠障碍。同样清楚的是，无牙患者在夜间睡眠时的磨牙水平低于正常的有牙受试者，如果它是功能稳定的，他们不太可能在夜间睡眠时出现磨牙引起的咀嚼功能障碍。