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Development of artificial urethra valve using shape memory alloy for the incontinence prevention

开发使用形状记忆合金的人工尿道瓣膜以预防失禁

基本信息

批准号：
08458293
负责人：
KOYAMA Hiroyuki
金额：
$ 4.16万
依托单位：
Shibaura Institut of Technology
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08458293/
关键词：
Incontinence Incontinence prevention Artificial musculus sphincter urethrae Artificial urethra valve Urethra tighrening pressure Shape memory alloy Rechargeble In vivo embedding 尿道括約筋流量可変締め付け圧力可変型

项目摘要

This study tightens urethra generally, it opens in the voidance urethra, and it is a purpose to develop the valve which low variably cuts the tightening pressure under sleeping for the necrosis prevention of the urethra. This valve was the internal embedded, and shaoe memory alloy and silicon resin were used in the operation of the valve. Research items and results of carrying out in this study are follows.(1) By the characteristics test of shape memorry ally considering using in vivo, recovery temperature and shape memory alloy, and the possibility as an actuator was examined.(2) Stress-strain curve of the tensiletest was simulated in order to control the movement of shape memorry ally, and the possibility as an actuator was examined.(3) From characteristics result and simulation result of the shape memory alloy, two artificial urethra valves were developed. One is artificial urethra valve of the U-type, and the elliptic in another.(4) Elliptic experiment for movement confirmation of the artificial urethra valve and leakage condition of the valve using the simulation urethra model with the U-type.(5) As a resuly of low variably cutting the tighening pressure under sleeping. the variety of the tightening pressure was realized by combining two elliptic valves.Though the artificial urethra valve fir the animal experiment ont he assumption of the dog has been completed, further resuarch is necessary, because it has not come to it in the animal experiment evaluation. By this study, not only that it prevents the incontinence but also that it controls the quantity of the voidance became possible, and the possibility of the incontinence patient of the severity was developed shape memory alloy silicon resin artificial urethra valve.

本研究对尿道进行一般性的紧缩，在排尿尿道处开放，目的是研制睡眠状态下低切应力的紧缩阀，以防止尿道坏死。该瓣膜为内埋式瓣膜，使用邵氏记忆合金和硅树脂。本研究的研究项目和实施结果如下。(1)通过在体应用、恢复温度和形状记忆合金的形状记忆特性测试，考察了其作为致动器的可能性。(2)模拟了拉伸试验的应力-应变曲线，以实现形状记忆控制运动，并探讨了其作为驱动器的可能性。(3)根据形状记忆合金的特性和模拟结果，研制了两种人工尿道瓣膜。一种是U型人工尿道瓣，另一种是椭圆型人工尿道瓣。(4)利用U型模拟尿道模型进行椭圆实验，验证人工尿道瓣膜的运动和瓣膜的泄漏情况。(5)作为低血压的结果，减少了睡眠时紧张的压力。通过组合两个椭圆形瓣膜来实现收紧压力的变化，虽然假设狗的动物实验已经完成，但由于在动物实验评价中尚未达到这一水平，因此还需要进一步研究。通过本研究，不仅可以防止尿失禁，而且可以控制排尿量，并且可以开发形状记忆合金硅树脂人工尿道阀，用于严重失禁患者。