Development ofnew three-dimensional jaw bone examination and evaluation systems for the optimum implant selection

开发新型三维颌骨检查和评估系统，以选择最佳种植体

• 批准号: 08557109
• 负责人: WADAMOTO Masayoshi
• 金额: $ 11.9万
• 依托单位: HIROSHIMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08557109/
• 关键词: pQCT; implant; monkey; bone quality; three-dimentional; bone mineral density; 骨接触率; pQCT; 三次元構築; CT

we measured bone mineral density in the mandibular edentulous jaw (M_1P_2P_1|P_1P_2M_1) of four monkeys, with an image analysis system (peripheral Quantitative Computed Tomography (pQCT) apparatus) for the bone volume evaluation. Three of four monkeys were measured bone mineral density immediately before implant insertion after three months of extraction, one of them were done after one, two and three months of post-extraction.Although the mean of 2.55% of photography errors was occurred by pQCT apparatus, the reappearance accuracy as much as conventional specification computed tomography was obtained. Significant correlation was recognized with coefficient of correlation r=0.78 between the bone quality classification (Lekholm et al.) by operation findings and bone mineral density of implant sites (P<0.01).It is recognized significant correlation with coefficient of correlation r=0.64, as the contrast between bone mineral density and the three-dimensional histologic evaluation of implant placement site by three-dimensional jaw bone examination are carried out (P<0.05). In other words, it is obvious that when bone mineral density of the cancellous bone is 400-600 mg/cm^3, the bone contact ratio is around 50%, when the bone mineral density is more than 800 mg/cm^3, the bone contact ratio be over 60%.The development of three-dimensional jaw bone examination and evaluation systems that give such suggestion that selects an optimum implant corresponding to the bone quality, by changing loading conditions after the insertion of implant or implant design from now on, is produced.

我们测量了下颌无牙颌（M_1P_2P_1）的骨密度|P_1P_2M_1），使用图像分析系统（外周定量计算机断层扫描（pQCT）装置）进行骨体积评估。四只猴子中有三只在拔牙三个月后植入种植体前立即测量了骨密度，其中一只在拔牙后一个月、两个月和三个月后测量了骨密度。尽管pQCT设备平均出现2.55%的摄影误差，但再现精度与传统规格的计算机断层扫描一样高。骨质量分类之间的相关系数r=0.78（Lekholm等人），骨密度与种植体植入部位三维颌骨检查的三维组织学评价有显著相关性（P <0.05），相关系数r=0.64。换句话说，很明显，当松质骨的骨矿物质密度为400-600 mg/cm^3时，骨接触率为50%左右，当骨矿物质密度大于800 mg/cm^3时，骨结合率可达60%以上。三维颌骨检查和评估系统给出选择与骨质量相对应的最佳植入物的建议，从现在开始，通过在植入物插入或植入物设计之后改变加载条件来生产。