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A study to elucidate the neural mechanism for the execution of voluntary movement in humans using magnetoencephalography electroencephalography, and evoked potentials

一项利用脑磁图、脑电图和诱发电位来阐明人类执行随意运动的神经机制的研究

基本信息

批准号：
08670741
负责人：
KANEOKE Yoshiki
金额：
$ 1.47万
依托单位：
Okazaki National Research Institutes
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1998
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08670741/
关键词：
visual system apparent motion human Visual motion higher brain function magnetoencephalography reaction time 色覚

项目摘要

This study was to elucidate the neural mechanism underling the execution of human voluntary movement in reaction to the visual stimuli using magnetoencephalography (MEG).In the first experiment, we investigated whether MEG can detect different responses to the different visual stimuli, such as motion and color.MEG response to the color change occurred at about 200 ms and was estimated to originate from the fusiform gyrus.In contrast, MEG response to the apparent motion stimuli occurred at about 150 ms and was estimated to originate from the visual motion area in humans.The next study was to investigate the relation between the human reaction time to execute motion in response to the apparent motion stimuli and the magnetic response to the same stimuli.The results indicated that our subjects seemed to respond to the neural activity in the human visual motion area caused by the apparent motion stimuli with the latency of 64 ms.In the third experiment, we varied the quality of smoothness of apparent motion by changing the stimulus timing.MEG responses to these stimuli showed their strength change related to the subjective rating of quality of motion.The results indicate that the result of visual information process is represented in the neural activities in a localized cortical area.We are planning to do a study to investigate the relation between human reaction time and magnetic response to apparent motion stimuli when the quality of motion is varied.

本研究旨在利用脑磁图（MEG）阐明人类对视觉刺激做出自主运动的神经机制。在第一个实验中，我们研究了MEG是否可以检测到对不同视觉刺激（例如运动和颜色）的不同反应。MEG对颜色变化的反应发生在大约200 ms，估计源自梭状回。相比之下，MEG对视运动的反应刺激发生在大约 150 毫秒，估计源自人类的视觉运动区域。接下来的研究是调查人类响应视运动刺激而执行运动的反应时间与对相同刺激的磁响应之间的关系。结果表明，我们的受试者似乎对潜伏期为 64 毫秒的视运动刺激引起的人类视觉运动区域的神经活动做出反应。在第三个实验中，我们改变了通过改变刺激时间来调节表观运动的平滑度。MEG对这些刺激的反应显示出与运动质量的主观评价相关的强度变化。结果表明，视觉信息处理的结果体现在局部皮质区域的神经活动中。我们计划进行一项研究，以调查当运动质量变化时，人类反应时间和对表观运动刺激的磁反应之间的关系。