An experimental study : Transfer of a pedicled venous flap containing perivenous areolar tissue and nerve.

一项实验研究：移植含有静脉周围乳晕组织和神经的带蒂静脉瓣。

• 批准号: 08671684
• 负责人: INADA Yuji
• 金额: $ 1.41万
• 依托单位: Nara Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08671684/
• 关键词: Venous flap; Pedicled flap; Nerve; Venous Hap; areolar tissue; venous flap

we evaluated experimentally the feasibility of transferring a pedicled venous flap with perivenous areolar tissue into an ectopic site, and investigated the role of each vein, the perivenous areolar tissue and nerve in the viability of pedicle venous flaps. Five groups of flaps were created Group 1 : (N=11) containing perivenous areolar tissue and a draining vein ; Group 2 : (N=10) perivenous areolar tissue, a draining vein and nerve ; Group 3 : (N=1O) only perivenous areolar tissue ; Group 4 : (N=6) perivenous areolar tissue and nerve ; Group 5 : (N=6) only draining vein.Macroscopic, angiographic and histological assessments were performed 14 days after transfer. Total survival area including superficial necrosis of Group 1,2,3,4 and 5 were 52.7%, 825%, 0%, 225% and 0% respectively. There were significant differences in mean survival area and mean total survival area including superficial necrosis between Group 1 and Group 2 (p(]SY.di-substituted right.[)O.O5). In contrast, all flaps in Group 3 and Group 5 became necrotic. These data suggest that a preserved vein is the necessary condition and additional arterial flow through the preserved nerve and a small vascular network within the areolar tissue may play an important role in flap survival.

摘要本研究探讨以静脉周围网状组织为蒂之静脉皮瓣转移至异位部位之可行性，并探讨静脉、静脉周围网状组织及神经在静脉皮瓣成活中之作用。制作了五组皮瓣：第1组：（N=11）含有静脉周围网状组织和引流静脉;第2组：（N=10）静脉周围网状组织、引流静脉和神经;第3组：（N= 10）仅静脉周围网状组织;第4组：（N=6）静脉周围网状组织和神经;第5组：（N = 10）静脉周围网状组织和神经。移植后14天进行大体、血管造影和组织学评估。第1、2、3、4、5组总存活面积（包括浅表坏死）分别为52.7%、82.5%、0%、22.5%、0%。第1组和第2组之间的平均存活面积和平均总存活面积（包括表面坏死）存在显着差异（p（]SY。双取代右。[）O.O5）。相反，第3组和第5组的所有皮瓣均坏死。这些数据表明，保留静脉是必要的条件和额外的动脉流量通过保留的神经和小血管网内的乳晕组织可能在皮瓣的生存发挥重要作用。

项目成果

Murata K: "Transfer of the pedicled venous flap with perivenous areolar tissue and nerve : an experimental study and clinical applications in the hand." Proceeding of 7th congress of the international federation of societies for surgery of the hand.787-79

Murata K：“带有静脉周围乳晕组织和神经的带蒂静脉皮瓣的移植：手部的实验研究和临床应用。”

Keiichi Murata et al: "Reversed Pedicled Venous Flap Containing Perivenous Areolar Tissue and/or Nerve in Hand" Inaugural Scientific Meeting of the Asian Pacific Federation of Societies for Surgery of the Hand (Perth, Australia, 22-26 March, 1997).

Keiichi Murata 等人：“包含静脉周围乳晕组织和/或手部神经的反向带蒂静脉皮瓣”亚太手外科学会联合会首届科学会议（澳大利亚珀斯，1997 年 3 月 22-26 日）。

村田,景一: "手背静脈を利用したVAF(Veno-adipofascial pedicled fasciocutaneous)Flapの1例" 整形災害外科. 38. 1221-1224 (1995)

Keiichi Murata：“使用手背静脉进行 VAF（静脉脂肪筋膜蒂筋膜）皮瓣的病例”整形外科。 38. 1221-1224 (1995)

K.Murata,Y.Inada,A.Fukui,et al: "Trarrsfer of the pedicked venous flcp with perivenous areolar tissue and Nence:An expenmeutal study and clinicel application in the Hand." 7th Congress of the International Federation of Societies for Surgery of the Hand(V

K.Murata、Y.Inada、A.Fukui 等人：“带有静脉周围乳晕组织和 Nence 的带蒂静脉 flcp 的转移：一项实验研究和手部临床应用。”

Murata K: "Transfer of a pedicled venous flap containing perivenous areolar tissue and nerve: An experimental study" British Jounal of Plastic Surgery. 52(in press). (1999)

Murata K：“含有静脉周围乳晕组织和神经的带蒂静脉皮瓣的移植：一项实验研究”《英国整形外科杂志》。