An experimental study : Transfer of a pedicled venous flap containing perivenous areolar tissue and nerve.

我们从实验上评价了带静脉乳晕组织的静脉皮瓣异位移植的可行性，并研究了每条静脉、静脉周围乳晕组织和神经在带蒂静脉皮瓣存活中的作用。共制作5组皮瓣：第1组11块，含静脉周围组织和引流静脉；第2组：静脉周围组织、引流静脉和神经；第3组：仅含静脉周围乳晕组织；第4组：6块静脉周围组织和神经；第5组：仅引流静脉。组1、组2、组3、组4、组5的总存活率分别为52.7%、825%、0%、225%和0%。第1组和第2组的平均存活面积和平均总存活面积(含浅层坏死)差异有统计学意义(P<0.05)。相反，第3组和第5组的皮瓣全部坏死。这些数据表明，保留静脉是必要条件，通过保留的神经和乳晕组织内的小血管网络的额外动脉流动可能对皮瓣存活起重要作用。

we evaluated experimentally the feasibility of transferring a pedicled venous flap with perivenous areolar tissue into an ectopic site, and investigated the role of each vein, the perivenous areolar tissue and nerve in the viability of pedicle venous flaps. Five groups of flaps were created Group 1 : (N=11) containing perivenous areolar tissue and a draining vein ; Group 2 : (N=10) perivenous areolar tissue, a draining vein and nerve ; Group 3 : (N=1O) only perivenous areolar tissue ; Group 4 : (N=6) perivenous areolar tissue and nerve ; Group 5 : (N=6) only draining vein.Macroscopic, angiographic and histological assessments were performed 14 days after transfer. Total survival area including superficial necrosis of Group 1,2,3,4 and 5 were 52.7%, 825%, 0%, 225% and 0% respectively. There were significant differences in mean survival area and mean total survival area including superficial necrosis between Group 1 and Group 2 (p(]SY.di-substituted right.[)O.O5). In contrast, all flaps in Group 3 and Group 5 became necrotic. These data suggest that a preserved vein is the necessary condition and additional arterial flow through the preserved nerve and a small vascular network within the areolar tissue may play an important role in flap survival.