An experimental study : Transfer of a pedicled venous flap containing perivenous areolar tissue and nerve.

摘要本研究探讨以静脉周围网状组织为蒂之静脉皮瓣转移至异位部位之可行性，并探讨静脉、静脉周围网状组织及神经在静脉皮瓣成活中之作用。制作了五组皮瓣：第1组：（N=11）含有静脉周围网状组织和引流静脉;第2组：（N=10）静脉周围网状组织、引流静脉和神经;第3组：（N= 10）仅静脉周围网状组织;第4组：（N=6）静脉周围网状组织和神经;第5组：（N = 10）静脉周围网状组织和神经。移植后14天进行大体、血管造影和组织学评估。第1、2、3、4、5组总存活面积（包括浅表坏死）分别为52.7%、82.5%、0%、22.5%、0%。第1组和第2组的平均存活面积和平均总存活面积（包括浅表坏死）差异有统计学意义（p <0.05）。[）O.O5）。相反，第3组和第5组的所有皮瓣均坏死。这些数据表明，保留静脉是必要的条件和额外的动脉流量通过保留的神经和小血管网内的乳晕组织可能在皮瓣的生存发挥重要作用。

we evaluated experimentally the feasibility of transferring a pedicled venous flap with perivenous areolar tissue into an ectopic site, and investigated the role of each vein, the perivenous areolar tissue and nerve in the viability of pedicle venous flaps. Five groups of flaps were created Group 1 : (N=11) containing perivenous areolar tissue and a draining vein ; Group 2 : (N=10) perivenous areolar tissue, a draining vein and nerve ; Group 3 : (N=1O) only perivenous areolar tissue ; Group 4 : (N=6) perivenous areolar tissue and nerve ; Group 5 : (N=6) only draining vein.Macroscopic, angiographic and histological assessments were performed 14 days after transfer. Total survival area including superficial necrosis of Group 1,2,3,4 and 5 were 52.7%, 825%, 0%, 225% and 0% respectively. There were significant differences in mean survival area and mean total survival area including superficial necrosis between Group 1 and Group 2 (p(]SY.di-substituted right.[)O.O5). In contrast, all flaps in Group 3 and Group 5 became necrotic. These data suggest that a preserved vein is the necessary condition and additional arterial flow through the preserved nerve and a small vascular network within the areolar tissue may play an important role in flap survival.