RESEARCH FOR DEVELOPMENT OF BIOMECHANICAL DENTAL IMPLANT WITH ARTIFICIAL PERIODONTAL LIGAMENT

(1)杂交型牙周韧带的研制本研究的目的是证实重组人骨形态发生蛋白-2(rhBMP-2)复合3 mm宽纤维胶原膜(FCM)对Beagle犬再植牙的再生作用。对3只Beagle犬的24颗前磨牙进行根管治疗后仔细拔除。在再植前，在牙根中部周围的带状区域(宽度3 mm)部分去除牙周膜和牙骨质，并用FCM/rhBMP-2覆盖根管牙本质裸露区域。(2)人再植和移植牙牙周膜的影像诊断：再植后2周和移植后4周，牙周膜的正常间隙得到确认。(3)再植牙牙周组织的再生情况。断定再植后4周的牙周膜再生与对照牙相当。

(1)Development Hybrid Type of Periodontal LigamentThe purpose of this study is to confirm the regeneration in the replanted tooth of Beagle dog by rhBMP-2 combined with ribbon (3 mm width) of fibrous collagen membrane (FCM). Twenty-four premolars of three beagle dogs were carefully extracted after thier root canals were treated. Before replantation their periodontal ligament and cementum were partially removed in a belt-type area (3 mm width) around the middle part of the root, and the denuded areas of root dentin were covered with FCM/rhBMP-2. It was concluded that combination of rhBMP-2 and FCM incduces periodontal ligament and cementum in the replanted tooth.(2)Diagnostic Imaging by Radiographs for Periodontal Membrane of Replanted and Transplanted tooth in HumanWe concluded that the normal space of periodontal membrane comfirmed 2-weeks fter the replantation and 4-weeks after the transplantation.(3)Periodontal regeneration in replanted tooth in rabit.We comfirmed the regeneration of priodontalligament 4-weeks after replantation was equivalent to the control tooth.