Development of 4-dimentional image construction for sequential chest radiograph.

连续胸片 4 维图像构建的开发。

• 批准号: 10670834
• 负责人: SANADA Shigeru
• 金额: $ 2.05万
• 依托单位: Kanazawa University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10670834/
• 关键词: Chest radiography; Computer-aided diagnosis; Temporal subtraction; 胸部X線画像法; コンピュータ支援診断; 時間的差分法; Image processing

To aid radiologists in the diagnosis of screening chest radiographs, a temporal subtraction technique using digital image processing was developed. The accurate image registration of two sequential images enables us to detect even subtle changes in the "difference image" between them. In this study, a new method based on matching "lung markings" is introduced.Twenty-nine pairs of sequential posteroanterior chest radiographs with and without the temporal changes were selected from cases taken with the computed radiography system. Image registration was employed with the local matching of "lung markings" in previous and current radiographs. Observer performance tests with and without indicating the "difference image" between them was carried out by eight radiologists.Observer performance with the temporal subtraction image shows that six of eight observers diagnosed with higher sensitivity (mean, 43.9% to 55.3%) and comparable false positive response. Mean area under the AFROC (Alternative Free-Response Receiver Operating Characteristics) curve also improved from 0.596 to 0.647 showing statistical significance.The subtraction image using this registration technique improves the diagnostic accuracy for subtle temporal changes.

为了帮助放射科医生通过胸部X光检查进行诊断，开发了一种使用数字图像处理的时间减法技术。两个连续图像的精确图像配准使我们能够检测它们之间“差异图像”的细微变化。在这项研究中，介绍了一种基于匹配“肺纹理”的新方法。从使用计算机X线摄影系统拍摄的病例中选择了29对有和没有时间变化的连续后前位胸部X线照片。图像配准与先前和当前射线照片中“肺部标记”的局部匹配一起使用。八名放射科医生进行了有或没有指示他们之间“差异图像”的观察者表现测试。时间减影图像的观察者表现表明，八名观察者中有六人诊断出较高的敏感性（平均为 43.9% 至 55.3%）和类似的假阳性反应。 AFROC（替代自由响应接收器操作特性）曲线下的平均面积也从 0.596 提高到 0.647，显示出统计显着性。使用这种配准技术的减影图像提高了细微时间变化的诊断准确性。

项目成果

Sanada, Shigeru: "Computer-aided diagnosis in detection of temporal changes for sequential chest radiographs."Nippon Acta Radiologica. 58(14). 824-830 (1998)

Sanada, Shigeru：“计算机辅助诊断，用于检测连续胸部 X 光片的时间变化。”Nippon Acta Radiologica。

Sanada S, Kobayashi T, Takashima T, Matsui T: "Enhancement of anormalies for temporally sequential chest radiography : Automated image registration and temporal subtraction technique."Japanese Journal of Radiological Technology. 55(1). 60-67 (1999)

Sanada S、Kobayashi T、Takashima T、Matsui T：“时间顺序胸部放射线照相异常的增强：自动图像配准和时间减法技术。”日本放射技术杂志。

Sanada S, Kobayashi T, Yoshida M, Matsui T, Takashima T: "Temporal subtraction technique for detection of subtle anomalies on temporally sequential bone-subtracted chest radiograph by energy subtraction."Japanese Journal of Radiological Technology. 56(3).

Sanada S、Kobayashi T、Yoshida M、Matsui T、Takashima T：“通过能量减法检测时间顺序骨减胸X光片上细微异常的时间减法技术。”日本放射技术杂志。

真田 茂: "肺紋理を対象とした画像位置合わせ法―胸部X線画像の時間的差分法"日本放射線技術学会雑誌. 56・3. 398-404 (2000)

Shigeru Sanada：“肺部图案的图像对准方法 - 胸部 X 射线图像的时间减法”日本放射线技术学会杂志 56・3（2000 年）。

真田 茂: "時系列胸部X線画像の差分処理画像を用いるコンピューター支援診断法の開発" 日本医学放射線学会雑誌. 58・14. 824-830 (1998)

Shigeru Sanada：“使用差分处理的时间序列胸部 X 射线图像的计算机辅助诊断方法的开发”日本医学放射学会杂志 58・14（1998 年）。