Sport scientific approach on the healthy society for ageing - Relation between the immune response and exercise for health -

健康老龄化社会的运动科学方法 - 免疫反应与健康运动之间的关系 -

• 批准号: 10680065
• 负责人: MASUHARA Mitsuhiko
• 金额: $ 1.98万
• 依托单位: Osaka University of Health and Sport Sciences
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1998
• 资助国家: 日本
• 起止时间: 1998 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-10680065/
• 关键词: immune response; ageing; PWC85%HRmax; physical fitness; 細胞性免疫; 筋収縮; 全身持久能力; リンパ球幼若化反応; インターロイキン; 運動; 高齢者; リンパ球; PHA; CD4; CD8; NK

This study was performed to determined the relationship between the immune response and exercise for health on ageing . The subjects were 10 healthy male of 59 〜 81 years old. They had physical fitness test, measurement of blood components and analysis of lymphocyte subsets.The summary of the results were as follows.1. The grip strength decrease with the ageing(p<0.05), but PWC85%HRmax of scale of endurance ability was independent of ageing. This results suggest that endurance ability is possible to be influenced by the exercise of everyday life.2. We observed that relation between grip strength and total serum protein, and CD4 of lymphocyte subsets were significant on the ageing (respectively p<0.05, p<0.01).3. This results suggested that the Cellular immune response depend on the protein of muscle and blood.4. A high correlation was seen between CD8 of lymphocyte subsets and triglyceride(p<0.05). This result suggest that hyperlipemia increase the suppressor lymphocyte subset.

进行这项研究是为了确定免疫响应与健康对衰老的健康之间的关系。受试者是59至81岁的10名健康男性。他们进行了身体适应性测试，对血液成分的测量和淋巴细胞子集的分析。结果的摘要如下1。随着衰老的降低（p <0.05），但PWC85％的耐力能力量表与衰老无关。结果表明，耐力能力可能会受到日常生活的行使的影响2。我们观察到，握力强度与总血清蛋白之间的关系，淋巴细胞亚群的CD4在衰老中显着（分别为p <0.05，p <0.01）。3。该结果表明细胞免疫反应取决于肌肉和血液的蛋白质4。在淋巴细胞亚群和甘油三酸酯的CD8之间观察到很高的相关性（P <0.05）。该结果表明高脂血症增加了抑制剂淋巴细胞亚群。

项目成果

Nieman DC, Ahle JC, Henson DA et al.: "Indomethacin does not alter the natural killer cell response to 2.5 hours of running"J. Appl. Physiol.. 79. 748-755 (1995)

Nieman DC、Ahle JC、Henson DA 等人：“吲哚美辛不会改变自然杀伤细胞对 2.5 小时跑步的反应”J.

増原光彦: "体育専攻女子学生の網状赤血球動態の特性と運動性貧血について"体力科学. 36. 791-791 (1992)

增原光彦：“女体育生的网织红细胞动力学特征和运动性贫血”《体能科学》36. 791-791（1992）。

増原 光彦: "The Nagano Symposium on Sports Sciences" Cooper Publishing Group,carmel,IN,USA, 646(6) (1998)

Mitsuhiko Masuhara：“长野体育科学研讨会”库珀出版集团，卡梅尔，印第安纳州，美国，646（6）（1998）

増原 光彦: "Effefcts of Physical Exercise on the Lymphocytic Response in Middle Age Men" J.American Society of Hematology. 76. 2130 (1991)

Mitsuhiko Masuhara：“体育锻炼对中年男性淋巴细胞反应的影响”J.American Society of Hematology 76. 2130 (1991)。

増原光彦: "スポーツ選手の膝障害と大腿部筋力に関する基礎的研究"日本総合健診医学会誌. 22. 367-375 (1995)

Mitsuhiko Masuhara：“运动员膝盖疾病和大腿肌肉力量的基础研究”日本一般健康检查医学会杂志 22. 367-375 (1995)。