Study on the Inhibition of Diabetic Cataract by Food Components

糖尿病患者发生糖基化（美拉德反应）和脂质过氧化两个重要反应。这两种反应导致糖尿病患者的血管系统并发症和白内障。在本研究中，抗氧化剂如原花青素、生育酚和儿茶素被使用。将这些抗氧化剂给予STZ型糖尿病大鼠（Wistar，雄性）3个月后，测定血糖、糖蛋白、脂质过氧化、晶状体成分葡萄糖、果糖、山梨醇、脂质过氧化。结果表明，原花青素（0.1% ~ 0.5%）、生育酚（100ppm）、儿茶素（0.1%）对糖尿病并发症，尤其是白内障有明显的抑制作用。

STUDY ON THE INHIBITION OF DIABETIC CATARACT BY FOOD COMPONENTSIn Diabetes Mellitus, two important reactions, namely, glycation (Maillard reaction) and lipid peroxidation occur. These two reactions lead to the complication of diabetic patients in the vascular system and the cataract. In this study, antioxidants such as proanthocyanidin, tocopherol and catechin were used.These antioxidant were administered to STZ diabetic rats (Wistar, male) for 3 months, then blood glucose, glycohemoglobin, lipid peroxidation, components of lens such as glucose, fructose, sorbitol, lipid peroxidation were measured. The results showed that proanthocyanidin (0.1%-0.5% in the diet), tocopherol (100ppm), catechin (0.1%) are effective in the inhibition of diabetic complication, especially, cataract.