Protection Systems in Plant Cells -- A Mechanism of Apoptosis with Monoterpenoids
Protection Systems in Plant Cells -- A Mechanism of Apoptosis with Monoterpenoids
批准号:
10680568
负责人:
IZUMI Shunsuke
金额:
$2.3万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999
中文摘要
investigate the defense mechanism of plant cells against chemical stress我们有screened various isoprenoids for inducers of apoptosis in cultured plant cells such astabacco, chamomile, celery, soybean,这些研究已经revealed that geraniol has the most potent apoptosis-inducingactivity, as judged from DNA fragmentation in the cells. However,D16 - D1-(Δ D12 - D1-isopentenyl)adenosine and kinetin prevented the geraniol-induced DNAfragmentation in the cells.Furthermore, cycloheximide and actinomycin D,inhibitors of protein and RNA syntheses, respectively没有suppress the apoptosis of the plant cells. This result suggests that the apoptotic processinduced by geraniol does not require the synthesis of new proteins。
英文摘要
To investigate the defense mechanism of plant cells against chemical stress, we have screened various isoprenoids for inducers of apoptosis in cultured plant cells such as tabacco, chamomile, celery, soybean, and liverwort. These studies have revealed that geraniol has the most potent apoptosis-inducing activity, as judged from DNA fragmentation in the cells. However, NィイD16ィエD1-(ΔィイD12ィエD1-isopentenyl)adenosine and kinetin prevented the geraniol-induced DNA fragmentation in the cells.Furthermore, cycloheximide and actinomycin D, inhibitors of protein and RNA syntheses, respectively, did not suppress the apoptosis of the plant cells. This result suggests that the apoptotic process induced by geraniol does not require the synthesis of new proteins.
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
T. Hirata: "A 20-KDa Protein with the GTP-Binding and Trypsin Inhibitory Activity from Glycine max"Biosci. Biotechnol. Biochem.. 63. 1816-1818 (1999)
T. Hirata:“来自大豆的具有 GTP 结合和胰蛋白酶抑制活性的 20-KDa 蛋白质”Biosci。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
S. Izumi: "Geroniol is a Potent Inducer of Apoptpsis-like Cell Death in the Cultured Shoot Primordia of Matricaria chamomilla"Biochem. Biophys. Res. Commun.. 259. 519-522 (1999)
S. Izumi:“Geroniol 是母菊培养芽原基中细胞凋亡样细胞死亡的有效诱导剂”Biochem。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
T. Hirata: "A symmetric hydrolysis of enol acetates with the Cultured Cells of Marchantia polymorpha"J. Molecular Catalysis B; Enzymatic. 5. 143-147 (1998)
T. Hirata:“用地钱培养细胞进行烯醇乙酸酯的对称水解”J。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
T. Hirata: "Epoxidation of Styrene with the peroxidase from the cultured Cells of Nicotiana tabaam"Tetrahedron. 54. 15993-16003 (1998)
T. Hirata:“用来自烟草培养细胞的过氧化物酶对苯乙烯进行环氧化”四面体。
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
Self-assembly of a membrane protein governed by the fluctuation of the anchor peptide and the self-organization.
-
批准号:22510231
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2010
-
负责人:IZUMI Shunsuke
-
依托单位:
Identification and topology analysis of plant odorant receptors
-
批准号:18510186
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.56万
-
财政年份:2006
-
负责人:IZUMI Shunsuke
-
依托单位:
Structure and Physiological Activity of Glycolipids from Amphibias
-
批准号:02640425
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.34万
-
财政年份:1990
-
负责人:IZUMI Shunsuke
-
依托单位:
国内基金
海外基金
登录
查看更多内容
Epac1/2通过蛋白酶体调控中性粒细胞NETosis和Apoptosis在急性肺损伤中的作用研究
-
批准号:LBY21H010001
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2020
-
负责人:郑绪阳
-
依托单位:
基于Apoptosis/Ferroptosis双重激活效应的天然产物AlbiziabiosideA的抗肿瘤作用机制研究及其结构改造
-
批准号:81703335
-
项目类别:青年科学基金项目
-
资助金额:20.0万元
-
批准年份:2017
-
负责人:卫高菲
-
依托单位:
双肝移植后Apoptosis和pyroptosis在移植物萎缩差异中的作用和供受者免疫微环境变化研究
-
批准号:81670594
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2016
-
负责人:陈昊
-
依托单位:
Serp-2 调控apoptosis和pyroptosis 对肝脏缺血再灌注损伤的保护作用研究
-
批准号:81470791
-
项目类别:面上项目
-
资助金额:73.0万元
-
批准年份:2014
-
负责人:董家鸿
-
依托单位:
Apoptosis signal-regulating kinase 1是七氟烷抑制小胶质细胞活化的关键分子靶点?
-
批准号:81301123
-
项目类别:青年科学基金项目
-
资助金额:23.0万元
-
批准年份:2013
-
负责人:王海莲
-
依托单位:
APO-miR(multi-targeting apoptosis-regulatory miRNA)在前列腺癌中的表达和作用
-
批准号:81101529
-
项目类别:青年科学基金项目
-
资助金额:22.0万元
-
批准年份:2011
-
负责人:陈雪芹
-
依托单位:
放疗与细胞程序性死亡(APOPTOSIS)相关性及其应用研究
-
批准号:39500043
-
项目类别:青年科学基金项目
-
资助金额:9.0万元
-
批准年份:1995
-
负责人:梁克
-
依托单位: