URINARY NAG ISOENZYMES IN COWS WITH EXPERIMENTALLY -INDUCED NEPHROSIS AND BOVINE CLINICAL CASES.

患有实验性肾病的奶牛的尿 NAG 同工酶和牛临床病例。

基本信息

  • 批准号:
    10839003
  • 负责人:
  • 金额:
    $ 2.43万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    1998
  • 资助国家:
    日本
  • 起止时间:
    1998 至 1999
  • 项目状态:
    已结题

项目摘要

This study was undertaken to determine the clinical usefulness of measurement of urinary NAG as a marker for renal diseases in animals. The results were as follows: (1) The individual values of urinary NAG index measured by using of 3 substrates ( 4MU, MCP and PNP) were correlated significantly with each other in cattle. There was no significant differences in mean values of urinary NAG index between bovine sexes, and neither amoung cows of various age groups. NAG index in urine samples obtained from cows with renal parenchymal lesions was higher than that obtained from healthy cows. (2) Urinary NAG isoenzymes were separated either by the mini column of DEAE-Sepharose CL6B or electrophoresis. The proportions of NAG-A and NAG-B in the urine of healthy cows and cats measured by mini column method or electrophoresis were 8 : 2 and 6.5 : 3.5, respectively, The proportion of NAG-A obtained in this study is similar to those in healthy parsons and rats. An increase of NAG-B was observed in the animals with renal parenchymal lesions. (3) Urinary NAG index in calves with nephrosis experimentally-induced with potassium dichromate was high and the increase of urinary NAG-B was observed. NAG-B of renal homogenate was also increased. In conclusion, the clinical usefulness of measurement of urinary NAG as a marker for renal diseases in animals was attested from the results obtained in this study.
本研究旨在确定测量尿 NAG 作为动物肾脏疾病标志物的临床实用性。结果如下:(1)用3种底物(4MU、MCP和PNP)测得的牛尿NAG指数个体值之间存在显着相关性。不同性别的牛之间以及不同年龄组的奶牛之间尿NAG指数的平均值没有显着差异。肾实质病变牛尿样中NAG指数高于健康牛尿样。 (2)尿液NAG同工酶通过DEAE-Sepharose CL6B微型柱或电泳分离。通过迷你柱法或电泳法测得健康牛和猫尿液中NAG-A和NAG-B的比例分别为8:2和6.5:3.5,本研究获得的NAG-A比例与健康帕森斯和大鼠的比例相似。在肾实质病变的动物中观察到 NAG-B 增加。 (3)重铬酸钾实验性肾病犊牛尿NAG指数较高,且尿NAG-B增加。肾匀浆的NAG-B也增加。总之,本研究的结果证明了测量尿 NAG 作为动物肾脏疾病标志物的临床实用性。

项目成果

期刊论文数量(29)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Reeko Sato: "Urine N-acetyl-β-D-glucosaminidase activity in healythy cattle"Am.J.Vet.Res.. 58・11. 1197-12000 (1998)
Reeko Sato:“健康牛的尿液 N-乙酰基-β-D-氨基葡萄糖苷酶活性”Am.J.Vet.Res. 58・11 (1998)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Reeko Sato: "N-acetyl-β-D-glucosaminidase activity in urine of cows with renal parenchymal lesions"Am.J.Vet.Res.. 60・4. 410-413 (1999)
Reeko Sato:“肾实质病变牛尿液中的 N-乙酰基-β-D-氨基葡萄糖苷酶活性”Am.J.Vet.Res. 60・4(1999)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
佐藤れえ子: "獣医診療 ハンドブック"インターズー. 5 (1999)
佐藤丽子:《兽医医学手册》Interzoo 5 (1999)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
NORIIO YAMAGISHI: "A parturient hypocalcemic cow with pathology of myocardial necrotic lesions and a history of milk fever."J. Anim. Clin. Med.. 8(3). 175-181 (1999)
NORIIO YAMAGISHI:“一头产后低钙血症奶牛,具有心肌坏死病变的病理学和乳热病史。”J.
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Jun Sato: "A case of Cushing's disease with hyperglycemia in a pony"J.Equine Sci.. 10・3. 17-20 (1999)
佐藤淳:“小马库欣病伴高血糖症”J.Equine Sci.. 10・3(1999)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

SATO Reeko其他文献

Retrospective study on intercurrent pancreatitis with <i>Babesia gibsoni</i> infection in dogs
吉氏巴贝虫感染犬并发胰腺炎的回顾性研究
  • DOI:
    10.1292/jvms.19-0280
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    1.2
  • 作者:
    MASUDA Misa;OTSUKA-YAMASAKI Yayoi;SHIRANAGA Nobuyuki;IGUCHI Aiko;UCHIDA Naohiro;SATO Reeko;YAMASAKI Masahiro
  • 通讯作者:
    YAMASAKI Masahiro

SATO Reeko的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('SATO Reeko', 18)}}的其他基金

Does the bovine lactoferrin improve chronic inflammation in the immuno-suppressive condition induced by FIV infection?
牛乳铁蛋白是否可以改善 FIV 感染引起的免疫抑制病症中的慢性炎症?
  • 批准号:
    16580261
  • 财政年份:
    2004
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
CLINICAL APPLICATION OF URINARY NAG INDEX AND SDS-PAGE ANALYSIS OF URINARY PROTEIN IN FELINE AND CANINE URINARY DISORDER
尿NAG指数和尿蛋白SDS-PAGE分析在猫科和犬类泌尿系统疾病中的临床应用
  • 批准号:
    12833003
  • 财政年份:
    2000
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

相似海外基金

Dairy Cow Heat Stress Within Building Microclimates
建筑微气候中的奶牛热应激
  • 批准号:
    BB/X009564/1
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Research Grant
'A bull and cow': the bovine in Victorian Britain, 1837-1901
“公牛和母牛”:维多利亚时代英国的牛,1837-1901 年
  • 批准号:
    2786923
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Studentship
Blood platelets: a key regulator of immune cross-talk of embryo with uterus toward cow pregnancy
血小板:胚胎与子宫对奶牛妊娠免疫串扰的关键调节因子
  • 批准号:
    22KF0017
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant-in-Aid for JSPS Fellows
Dairy cow heat stress within building microclimates
建筑微气候中的奶牛热应激
  • 批准号:
    BB/X008517/1
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Research Grant
Cow Recovery: The Sustainable Solution for Improving Downer Cow Outcomes
奶牛康复:改善情绪低落奶牛结局的可持续解决方案
  • 批准号:
    10082215
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant for R&D
Feasibility study of a unit for stall management within the dairy sector to reduce carbon impact and improve cow health
乳制品行业畜栏管理单元的可行性研究,以减少碳影响并改善奶牛健康
  • 批准号:
    10082833
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Collaborative R&D
Activation of sperm/uterine innate immune receptor TLR2 for high fertility after cow embryo transfer
激活精子/子宫先天免疫受体 TLR2 以提高奶牛胚胎移植后的高生育力
  • 批准号:
    22KF0018
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant-in-Aid for JSPS Fellows
Development of an Autonomous Robotic cow Cubicle bedding unit (AG ARC)
自主机器人牛舍垫料单元(AG ARC)的开发
  • 批准号:
    10041055
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Collaborative R&D
Dairy Cow Heat Stress Within Building Microclimates
建筑微气候中的奶牛热应激
  • 批准号:
    BB/X00824X/1
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Research Grant
Development of strict criteria for treatment of cow using digital radiography (DR)
制定使用数字射线照相 (DR) 治疗奶牛的严格标准
  • 批准号:
    23K05578
  • 财政年份:
    2023
  • 资助金额:
    $ 2.43万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了