Epidemiological study on osteoarthritis among community-dwelling women

我们研究了591名居住在日本长崎县大岛镇的女性骨关节炎和关节疼痛的患病率及其相关性。通过问卷调查收集关节疼痛信息。受试者被问到，在过去一个月的大部分时间里，你的哪个关节曾经疼痛、肿胀、疼痛或有触痛？在每个关节（肩膀、肘部、手腕、手/手指、臀部、膝盖、脚踝、脚、颈部、上背部、中背部和下背部）的骨骼图上，提供了针对身体两侧的回答框（是或否）。膝关节x线片（前后负重）。测量身高、体重，计算身体质量指数（BMI）。膝关节（34.8%）、腰背（26.6%）和肩部（16.4%）是关节疼痛最常见的部位。三分之一的女性患有膝关节骨性关节炎。在40-49岁年龄组中，没有女性有膝骨关节炎，但患病率随着年龄的增长而增加，在80岁及以上年龄组中，60%的女性患有膝骨关节炎。20%的女性有症状性膝骨关节炎。患病率随年龄增长而增加，40%有症状性膝骨关节炎。多变量logistic回归分析显示，影像学或症状性膝骨关节炎与年龄、肥胖、膝关节损伤史和体力活动增加有关。以往的研究报道，年龄增长、肥胖和膝关节损伤史是膝关节骨关节炎的危险因素，这与我们的研究结果一致。增加的体力活动可能归因于膝关节骨性关节炎的发展，通过关节软骨的附加负荷。

We studied 591 women living in Oshima town, Nagasaki Prefecture, Japan on the prevalence of osteoarthritis and joint pains and its association. Information on painful joints was collected by questionnaire. Subjects were asked Which of your joints have ever been painful, swollen, aching, or tender on most days for the past one month? Response boxes (yes and no) for both sides of the body were provided on an illustration of the skeleton for each joint (shoulders, elbows, wrists, hands/fingers, hips knees, ankles, feet, neck, upper back, mid-back, and low back). Radiographs were obtained of knees (antero-posterior weightbearing). Height and weight were measured, and body mass index (BMI) was calculated. Knee (34.8%), low back (26.6%) and shoulder (16.4%) pain were the most prevalent locations of joint pain. One third of women had radiographic osteoarthritis of the knee. None of the women had radiographic knee osteoarthritis in age group of 40-49 years, but the prevalence increased with age, and 60% of women had knee osteoarthritis in age group of 80 and over. Twenty percent of the women had symptomatic knee osteoarthritis. The prevalence increased with age, and 40% had symptomatic knee osteoarthritis. Multiple variable logistic regression analysis revealed that radiographic or symptomatic knee osteoarthritis was associated with increasing age, obesity, history of knee injury and increased phsical activity. Previous studies have been reported that increasing age, obesity and history of knee injury were risk factors for knee osteoarthritis, which is consistent with our results. Increased physical activity may attribute to development of knee osteoarthritis through additive loading to joint cartilage.