Analysis of flow and flow reserve in patients with arterial occlusive disease of lower extremities with MRI and CT

应用磁共振电影成像技术结合门控技术，对双侧股浅动脉血流峰值速度、平均血流速度和平均血流量进行了检测。这些数据与正常健康志愿者的数据进行了比较。血流图型分析中，患者组有少量回流，部分病例未见回流。在所有健康志愿者中均未发现逆流现象，运动应激后峰值流速、平均流速和平均流速均显著增加。多例峰值血流速度增快，所有患者返流均减少。受试者最大血流速度和平均血流速度增加率均高于患者组，但两组间差异无统计学意义。患者和健康志愿者的平均血流量(血流储备)增加率无显著差异。同时分析了患者和健康志愿者团注造影剂后的时间密度曲线。在注射造影剂后2分钟内连续采集双侧股骨的数据。骨骼肌的增强率低于血管，但高于脂肪组织。健康志愿者动脉注射造影剂后骨骼肌信号增强，注射造影剂后40~60s达平台期。病例组信号强度曲线呈渐进式增加，多数无平台型。因此，无法获得最陡峭的坡度值。左右两侧无显著差异。

The peak velocity, mean velocity and mean flow volume of bilateral superficial femoral arteries were evaluated in patients with arterial occlusive disease of the lower extremities, using cine MRI technique with EGG gating. Those data were compared with those of normal healthy volunteers. In analysis of flow pattern, reverse flow was small in patients group, and some cases, no reverse flow was noticed. Lack of reverse flow was not noticed in any healthy volunteer.Peak velocity, mean velocity and mean flow volume increased significantly after exercise stress. Peak velocity increased in many cases and reverse flow decreased in all cases. The increase rate of peak velocity and mean velocity was higher in volunteers than in patients group, but there was no statistically significant difference between the two groups. Also no significant difference between the increase rate of mean flow volume (flow reserve) of patients and-that of healthy volunteers.The time density curves after bolus administration of contrast material were also analyzed, both in patients and health volunteers. Continuous data acquisition of both femurs was obtained during 2 minutes just after contrast material injection. The enhancement rate of skeletal muscles was lower than vessels, but higher than fat tissue. In healthy volunteers the signal of skeletal muscle increased after artery, and reached plateau 40 〜 60 seconds after the beginning of contrast material injection. In patients group, the signal intensity curve showed gradual increase pattern and in many cases showed no plateau. Therefore steepest slope values could not be obtained. No significant difference was noticed between the right side and the left side