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THE MECHANISM OF ISCHEMIC TOLERANCE INDUCTION BY ADENOSINE IN FETAL CARDIAC MUSCLE

THE MECHANISM OF ISCHEMIC TOLERANCE INDUCTION BY ADENOSINE IN FETAL CARDIAC MUSCLE
腺苷诱导胎儿心肌缺血耐受的机制
批准号:
11671656
负责人:
SAWA Rintaro
金额:
$2.05万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2000

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中文摘要
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英文摘要
[PURPOSE] The purpose of this study is to evaluate the effect of adenosine on the induction of ischemic tolerance in fetal cardiac muscle.[METHOD] We measured cardiac adenosine and 5'-nucleotidase during ischemia with and without ischemic preconditioining in fetal sheep.[RESULTS] The significant elevation of cardiac adenosine after ischemic preconditioining was associated with an increase of 5'-nucleotidase activity.[CONCLUSION] This support the powerful effect.of adenosine on the induction of ischemic tolerance in fetal cardiac muscle.
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Suzuki S et al: "Changes in letal plasma adenosine and xanthine sencentrations during letal asphyxia with maternal oxygen administration in erves"Tohoku J Exp Med. 192. 275-281 (2000)
Suzuki S 等人:“在致死窒息期间母体给氧时致死血浆腺苷和黄嘌呤浓度的变化”Tohoku J Exp Med。
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通讯作者:
Yoneyama Y, et al.: "Plasma adenosine levels increase in normal pregnant women."Am J Obstet Gynecol. 182. 1200-3 (2000)
Yoneyama Y 等人:“正常孕妇的血浆腺苷水平增加。”Am J Obstet Gynecol。
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澤 倫太郎 他: "アデノシンによる胎仔心筋の虚血耐性機構の解明"日産婦誌. 52. 301(S-225) (2000)
Rintaro Sawa 等:“腺苷诱导的胎儿心肌缺血耐受机制的阐明”Nissan Gynecology. 52. 301(S-225) (2000)。
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通讯作者:
Takeuchi T et al: "Regulation of platelet aggregation in vitro by plasma adenosine in preeclampsia"Gynecol Obstet Invest. 51. 36-39 (2001)
Takeuchi T 等人:“先兆子痫中血浆腺苷对体外血小板聚集的调节”Gynecol Obstet Invest。
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22
    Application of Fetal Adenosine Activity in the Development of a New Drug-Eluting Stent
    • 批准号:
      22591838
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.58万
    • 财政年份:
      2010
    • 负责人:
      SAWA Rintaro
    • 依托单位:
    THE INDUCTION OF HIBERNATION OF FETAL CARDIOCYTE BY ADENOSINE
    • 批准号:
      14571588
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.92万
    • 财政年份:
      2002
    • 负责人:
      SAWA Rintaro
    • 依托单位:
    Mechanism of neuronal protection by adenosine in the fetus.
    • 批准号:
      08671937
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $0.96万
    • 财政年份:
      1996
    • 负责人:
      SAWA Rintaro
    • 依托单位: