Composition and role of cement line on the resorption surface of the tooth.

牙齿吸收表面上水泥线的成分和作用。

• 批准号: 11671825
• 负责人: SAHARA Noriyuki
• 金额: $ 2.18万
• 依托单位: Mastumoto Dental University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11671825/
• 关键词: Enamel; Cement line; Tooth resorption; Repair; TRAP; Shedding; Odontoclasts; Deciduous teeth

The present study suggested that a basophilic layer, cement line, on the previously resorbed enamel surface observed in the transitional phase may play a important role in the process of tooth resorption-sequence. The cement line on the resorbed enamel surface gradually matured and mineralized towards the end of the transitional phase, and ultimately formed reversal line that could be found between the resorbed enamel and the newly formed cementum-like tissue. Base on these results it can be assumed that the components of the basophilic layer on the resorbed dentine surface (cement line and reversal line) might be consisted from multiple sources : (1) secretory products of the odontoclasts, (2) circulating various plasma proteins, (3) secretory products mononuclear phagocytic cells on the resorbed surface and (4) secretary products of cementoblast-like cells. And further, it can be also postulated that these various components in this layer may also play multiple roles in various stages of tooth resorption-repair sequence : (a) Some of them will act as coupling factors to promote the proliferation and differentiation of cementoblast-like cells. (b) Some of them may serve to influence early matrix organization and mineralization. (c) They will be act as promoters for the interfacial adhesion between different mineralized tissues.

本研究提示，在牙釉质吸收的过渡阶段，牙釉质表面存在一层亲碱性的水泥线，可能在牙釉质吸收过程中起重要作用。在过渡期结束时，被吸收牙釉质表面的水泥线逐渐成熟矿化，最终在被吸收牙釉质与新形成的牙骨质样组织之间形成逆转线。基于这些结果，可以假设在被吸收的牙本质表面（水泥线和逆转线）上的嗜碱性层的成分可能由多种来源组成：(1)破牙细胞的分泌产物，(2)循环的各种血浆蛋白，(3)被吸收表面的单核吞噬细胞的分泌产物，(4)成水泥细胞样细胞的分泌产物。此外，我们还可以推测，这一层的各种成分在牙齿吸收修复过程的各个阶段也可能发挥多种作用：(a)它们中的一些会作为偶联因子促进成牙骨质样细胞的增殖和分化。(b)其中一些可能影响早期基质组织和矿化。(c)它们将作为不同矿化组织之间界面粘附的促进剂。